一般說明
磷酸酶抑制剂混合液 1 包括将抑制碱性磷酸酶的 L -同工酶以及丝氨酸/苏氨酸蛋白磷酸酶(如 PP1 和 PP2A)的抑制剂混合物。本品含微囊藻毒素LR、斑蝥素和(−)-p-溴四唑。磷酸酶抑制剂混合液1 已被替换为 P0044。
應用
磷酸酶抑制剂混合液1 已被用于核蛋白分离和电泳迁移率变动分析(EMSA)以激活连环链蛋白。它也已用于蛋白质印迹分析。
生化/生理作用
磷酸酶是许多重要生物过程的活性调节剂。小分子对磷酸酶的抑制有助于研究其生物学作用。
數量
推荐的用法是 100 倍稀释。
分析報告
检测牛肝脏、人胎盘和兔肌肉等动物组织的细胞提取物,以及 A431 和 Jurkat 细胞系的提取物。
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
188.6 °F
閃點(°C)
87 °C
其他客户在看
Mucosal immunology, 10(6), 1553-1568 (2017-04-13)
Virulent Mycobacterium tuberculosis (Mtb) triggers necrosis in host Mϕ, which is essential for successful pathogenesis in tuberculosis. Here we demonstrate that necrosis of Mtb-infected Mϕ is dependent on the action of the cytosolic Receptor Interacting Protein Kinase 3 (RIPK3) and
Aberrant Wnt/β-catenin signaling in pancreatic adenocarcinoma.
Neoplasia, 8(4), 279-289 (2006)
Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis.
Proceedings of the National Academy of Sciences of the USA, 103(28), 10606-10611 (2006)
Larger therapeutic window for steroid versus VEGF-A inhibitor in inflammatory angiogenesis: surprisingly similar impact on leukocyte infiltration.
Investigative Ophthalmology & Visual Science, 53(7), 3296-3302 (2012)
Nature, 467(7312), 214-217 (2010-09-11)
Dendritic cells serve a key function in host defence, linking innate detection of microbes to activation of pathogen-specific adaptive immune responses. Whether there is cell-intrinsic recognition of human immunodeficiency virus (HIV) by host innate pattern-recognition receptors and subsequent coupling to
商品
Information on Phosphatase Inhibitor Cocktail for researchers and students from MilliporeSigma. Phosphorylation is a reversible protein post-translational modification.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门