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产品名称
3-(2-氨乙酸)吲哚 盐酸盐, powder
化驗
≥98%
形狀
powder
顏色
white to off-white
mp
149-154 °C (lit.)
溶解度
H2O: 17 mg/mL
0.1 M HCl: 22 mg/mL
ethanol: 5.3 mg/mL
儲存溫度
2-8°C
SMILES 字串
Cl[H].NCCc1c[nH]c2ccc(O)cc12
InChI
1S/C10H12N2O.ClH/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;/h1-2,5-6,12-13H,3-4,11H2;1H
InChI 密鑰
MDIGAZPGKJFIAH-UHFFFAOYSA-N
基因資訊
human ... HTR3A(3359)
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一般說明
血清素普遍存在于所有动物中。它在中枢和外周神经系统中(CAN/PNS)发挥多样功能，是一种激素和丝裂原分子，血清素由大脑中的轴突终末生产。动作电位引发血清素释放，在突触中扩散结合到突触后受体引起神经反应。血清素在发育、呼吸、体温调节、内分泌、心血管和胃肠道功能中起重要作用。还在睡眠觉醒周期、性、情绪、记忆、攻击性、痛觉、学习和认知等感知觉行为中发挥作用。血清素影响多种精神障碍，包括精神分裂、神经性厌食症、抑郁，还影响强迫症、惊恐发作和社交恐惧症等焦虑障碍。血清素水平变化与药物滥用、赌博、注意力缺陷障碍、强迫症和冲动性的冲动相关障碍或人格障碍有关。
應用
盐酸血清素用于：研究5-羟色胺受体拮抗剂调节肝脏球状体纤维化的机制，研究其对人胚胎肾脏细胞细胞外信号调节激酶(ERK)磷酸化的影响，用于结肠癌细胞系的transwell试验、愈伤试验和肿瘤同种异体移植试验
生化／生理作用
神经递质。
特點和優勢
该化合物收录于 受体分类和信号转导手册的《生物胺转运体 》页面。想要浏览手册的其他页面， 请单击此处。
準備報告
溶液需新鲜配制。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Repr. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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