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Merck

G1796

Sigma-Aldrich

乙交酯

≥99%

别名:

1,4-二氧杂环-2,5-己二酮

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About This Item

经验公式(希尔记法):
C4H4O4
CAS号:
分子量:
116.07
EC號碼:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

品質等級

化驗

≥99%

mp

82-86 °C (lit.)

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

O=C1COC(=O)CO1

InChI

1S/C4H4O4/c5-3-1-7-4(6)2-8-3/h1-2H2

InChI 密鑰

RKDVKSZUMVYZHH-UHFFFAOYSA-N

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一般說明

乙交酯是α羟基酸的环状二聚体,可用于制备脂肪族聚酯。它通过甘醇酸的二聚化而合成。它可制备低毒的人造生物可降解聚合物,适于医疗应用。它主要用于通过开环聚合反应形成高度结晶的聚乙交酯。

應用

乙交酯可作为单体与丙交酯单体共聚制备聚乳酸-乙交酯共聚物(PGLA)。PGLA进一步用于以下应用:
  • 多孔PGLA微球支架应用于骨修复。
  • 封装PGLA纳米颗粒可用于药物输送和组织工程应用。因具有众多特性,包括生物可降解性、生物相容性、延长药物释放时间和保护药物不被降解,由PLGA制成的聚合物微/纳米颗粒引起了广泛关注。
也可用于合成聚乙二醇-己内酯(PGCL)共聚物,后者可作为生物可吸收缝合材料。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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