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产品名称
D -谷氨酸, ≥99% (TLC)
品質等級
化驗
≥99% (TLC)
形狀
powder
技術
ligand binding assay: suitable
顏色
white to off-white
mp
200-202 °C (subl.) (lit.)
SMILES 字串
N[C@H](CCC(O)=O)C(O)=O
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChI 密鑰
WHUUTDBJXJRKMK-GSVOUGTGSA-N
基因資訊
human ... CCR2(1231)
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一般說明
D-谷氨酸是细菌肽聚糖结构的必需成分。可通过D-谷氨酸添加酶（murD）将其加入UDP-N-乙酰胞壁酰-L-丙氨酸（UDP-MurNAc-L-丙氨酸）中。然后将其掺入肽聚糖前体中。 肽聚糖构成革兰氏阳性和阴性细菌的细胞壁。通过谷氨酸消旋酶（GR）将L-谷氨酸转化为D-谷氨酸是肽聚糖合成中必不可少的步骤。
應用
D-谷氨酸适用于GR酶（谷氨酸消旋酶）及其抑制剂的结构亲和关系（SAR）研究。
生化／生理作用
谷氨酸的非天然异构体。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
P Doublet et al.
Journal of bacteriology, 174(18), 5772-5779 (1992-09-01)
The murI gene of Escherichia coli, whose inactivation results in the inability to form colonies in the absence of D-glutamic acid, was identified in the 90-min region of the chromosome. The complementation of an auxotrophic E. coli B/r strain by
Katie L Whalen et al.
Molecular informatics, 30(5), 459-471 (2011-07-09)
Existing techniques which attempt to predict the affinity of protein-ligand interactions have demonstrated a direct relationship between computational cost and prediction accuracy. We present here the first application of a hybrid ensemble docking and steered molecular dynamics scheme (with a
Matthew Volgraf et al.
Nature chemical biology, 2(1), 47-52 (2006-01-13)
The precise regulation of protein activity is fundamental to life. The allosteric control of an active site by a remote regulatory binding site is a mechanism of regulation found across protein classes, from enzymes to motors to signaling proteins. We
H Persson et al.
Molecular and cellular biology, 10(9), 4701-4711 (1990-09-01)
The gene encoding glutamic acid decarboxylase (GAD), the key enzyme in the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid, is shown to be expressed in the testis of several different species. Nucleotide sequence analysis of a cDNA clone isolated from
Jia Luo et al.
Science (New York, N.Y.), 298(5592), 425-429 (2002-10-12)
The motor abnormalities of Parkinson's disease (PD) are caused by alterations in basal ganglia network activity, including disinhibition of the subthalamic nucleus (STN), and excessive activity of the major output nuclei. Using adeno-associated viral vector-mediated somatic cell gene transfer, we
Chromatograms
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