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Merck

219096

Sigma-Aldrich

D -天冬氨酸

99%, for peptide synthesis, ReagentPlus®

别名:

(R)-(-)-氨基琥珀酸, (R)-2-氨基琥珀酸

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About This Item

线性分子式:
HO2CCH2CH(NH2)CO2H
CAS号:
分子量:
133.10
Beilstein:
1723529
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.22

product name

D -天冬氨酸, ReagentPlus®, 99%

品質等級

產品線

ReagentPlus®

化驗

99%

形狀

powder

光學活性

[α]20/D −24°, c = 2.3 in 6 M HCl

光學純度

ee: 98% (GLC)

反應適用性

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

應用

peptide synthesis

SMILES 字串

N[C@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1

InChI 密鑰

CKLJMWTZIZZHCS-UWTATZPHSA-N

基因資訊

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應用


  • Metabolomics Analysis Identifies Differential Metabolites as Biomarkers for Acute Myocardial Infarction.: This study utilizes metabolomics to identify biomarkers for acute myocardial infarction, showcasing D-Aspartic acid′s role in amino acid metabolism and potential diagnostic applications. (Zhou et al., 2024).

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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Noriko Fujii et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3141-3147 (2011-07-05)
Homochirality is essential for life. L-Amino acids are exclusively used as substrates for the polymerization and formation of peptides and proteins in living systems. However, d-amino acids, which are enantiomers of L-amino acids, were recently detected in various living organisms
Yuhei Mori et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3303-3309 (2011-06-04)
UV-B irradiation is one of the risk factors in age-related diseases. We have reported that biologically uncommon D-β-Asp residues accumulate in proteins from sun-exposed elderly human skin. A previous study also reported that carboxymethyl lysine (CML; one of the advanced
Ikuhiko Noji et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3310-3316 (2011-07-12)
Unusual amino acid residues such as L-β-aspartyl (Asp), D-α-Asp, and D-β-Asp have been detected in proteins and peptides such as α-crystallin in the lens and β-amyloid in the brain. These residues increase with age, and hence they are associated with
H Homma
Amino acids, 32(1), 3-11 (2006-06-07)
Recent investigations have shown that D-aspartate (D-Asp) plays an important physiological role(s) in the mammalian body. Here, several recent studies of free D-Asp metabolism in mammals, focusing on cellular localization in tissues, intracellular localization, biosynthesis, efflux, uptake and degradation are
Tadatoshi Kinouchi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3349-3352 (2011-09-29)
The formation and accumulation of D-aspartate residue (D-Asp) in proteins caused by oxidative stress leads to dysfunction and/or denaturation of proteins, and is consequently responsible for aging-related misfolding diseases such as cataracts, prion disease, and Alzheimer's disease. We sought to

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