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Merck
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文件

F7131

Sigma-Aldrich

N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸

chromogenic, ≥99% (HPLC)

别名:

FAPGG, N-[3-（2-呋喃基）丙烯酰基]- L -苯丙氨酰-甘氨酰-甘氨酸

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About This Item

经验公式（希尔记法）:
C20H21N3O6
CAS号:
64967-39-1
分子量:
399.40
MDL號碼:
MFCD00036816
分類程式碼代碼:
12352202
PubChem物質ID:
24894929
NACRES:
NA.32

product name

N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸,

儲存溫度

−20°C

SMILES 字串

OC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c2ccco2

InChI

1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1

InChI 密鑰

ZDLZKMDMBBMJLI-FDMDGMSGSA-N

基因資訊

human ... ACE(1636) , ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421) , ACE2(70008) , ACE3(498012)

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Amino Acid Sequence

FA-Phe-Gly-Gly

一般說明

N-[3-（2-呋喃基）丙烯酰基]-Phe-Gly-Gly 作为血管紧张素转化酶 (ACE) 的底物，用于 ACE 的抑制试验。

應用

N-[3-（2-呋喃基）丙烯酰基] 苯基-Gly-Gly 已用于 ACE（血管紧张素转化酶）抑制活性的动力学分光光度法测定。

基底

连续分光光度法测定血管紧张素转化酶 (ACE) 的底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Md Yousof Ali et al.
Molecules (Basel, Switzerland), 24(21) (2019-11-07)
The bioactivity of ten traditional Korean Angelica species were screened by angiotensin-converting enzyme (ACE) assay in vitro. Among the crude extracts, the methanol extract of Angelica decursiva whole plants exhibited potent inhibitory effects against ACE. In addition, the ACE inhibitory
Zhen-Hao Li et al.
Scientific reports, 7(1), 12243-12243 (2017-09-28)
Quality control is critical for ensuring the safety and effectiveness of drugs. Current quality control method for botanical drugs is mainly based on chemical testing. However, chemical testing alone may not be sufficient as it may not capture all constituents
Anees A Syed et al.
Journal of ethnopharmacology, 193, 555-565 (2016-10-11)
Ulmus wallichiana Planchon (Himalayan Elm), a traditional medicinal plant, used in fracture healing in folk tradition of Uttarakhand, Himalaya, India. It is also used as diuretic. U. rhynchophylla, native to China, known as Gou Teng in Chinese medicine, is used
E Villard et al.
American journal of human genetics, 58(6), 1268-1278 (1996-06-01)
Plasma angiotensin I-converting enzyme (ACE) levels are highly genetically determined. A previous segregation-linkage analysis suggested the existence of a functional mutation located within or close to the ACE locus, in almost complete linkage desequilibrium (LD) with the ACE insertion/deletion (I/D)
T P Gorski et al.
Clinical chemistry, 37(8), 1390-1393 (1991-08-01)
For normal and above-normal concentrations of angiotensin-converting enzyme (ACE; EC 3.4.15.1) activity in plasma, results of a manual fluorometric method [with hippuryl-histidyl-leucine (HHL), 5 mmol/L, as substrate] correlated well with those of an automated spectrophotometric method [with 3-(2-furylacryloyl)-L-phenylalanyl-glycyl-glycine (FAPGG), 2
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