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無菌
sterile-filtered
品質等級
種類
Type I
形狀
saline solution
分子量
H subunit ~21 kDa
L subunit ~19 kDa
顏色
red to brown
正離子痕跡
Cd: ≤1% (as % of ferritin)
儲存溫度
2-8°C
一般說明
壳蛋白 24 个蛋白质亚基（脱铁铁蛋白）和核心 Fe 3+ 离子，肽 MW 为 440 kDa。回顾铁蛋白样铁储存蛋白超家族，在地球上的生命中几乎无处不在。
應用
来自马脾的铁蛋白已用于：
- 分枝杆菌生长测定
- 尺寸排阻色谱
- 标记巨噬细胞
- 作为 μ 介子自旋光谱学的参考标准
生化／生理作用
广泛的储铁蛋白在铁代谢中起关键作用。其用作细胞内的铁储备（特别是在脾脏、肝脏、肠粘膜和骨髓中）并参与铁解毒。 研究表明，铁蛋白铁的掺入是由与铁蛋白 H 亚基相关的铁氧化酶活性和与铁蛋白 L 亚基相关的成核中心介导的。 从铁蛋白释放铁在铁依赖性脂质过氧化中具有重要作用，并且可能在体内促成自由基诱导的细胞损伤。因此，通过结合铁，铁蛋白可以起抗氧化剂的作用。
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Shi Qiu et al.
Ultramicroscopy, 216, 113036-113036 (2020-06-17)
A new method for imaging liquid specimens with atom probe tomography (APT) is proposed by introducing graphene encapsulation. By tuning the encapsulation speed and the number of encapsulations, controllable volumes of liquid can be encapsulated on a pre-sharpened specimen tip
Adipocyte model of Mycobacterium tuberculosis infection reveals differential iron availability to bacilli in the lipid rich caseous environment
Nandy A, et al.
Infection and Immunity, IAI-00041 (2018)
Sella Kim et al.
Journal of molecular biology, 428(24 Pt B), 5007-5018 (2016-11-03)
Iron and oxygen chemistry is mediated by iron proteins for many biological functions. Carboxylate-bridged diiron enzymes including ferritin have the common mechanism of oxygen activation via peroxodiferric intermediates. However, the route for iron uptake and the structural identification of intermediates
Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria
Methods in Enzymology, 595, 107-160 (2017)
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Magnetic resonance in medicine, 87(3), 1276-1288 (2021-10-17)
To employ an off-resonance saturation method to measure the mineral-iron pool in the postmortem brain, which is an endogenous contrast agent that can give information on cellular iron status. An off-resonance saturation acquisition protocol was implemented on a 7 Tesla
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