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Merck

T9145

Sigma-Aldrich

甲状腺球蛋白 来源于牛甲状腺

(For Gel Filtration Chromatography)

别名:

Tg

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About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
23151820
NACRES:
NA.56

生物源

bovine thyroid

品質等級

形狀

powder

分子量

~670 kDa

技術

bioconjugation: suitable

UniProt登錄號

儲存溫度

−20°C

基因資訊

cow ... TG(280706)

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應用

Thyroglobulin is used for antibody purification and characterization. Thyroglobulin has been used in studies assessing the monitoring of differentiated thyroid cancer as well as to develop an accurate diagnostic tool for patients with autoimmune thyroid diseases.
通常用作生产抗体的载体蛋白。其优点在于大量的酪氨酸残基可用于重氮反应进行偶联。

生化/生理作用

储存在甲状腺中的含碘蛋白质。当甲状腺受到来自垂体的促甲状腺激素(TSH) 的刺激时,转化为循环甲状腺素。因为其表达是甲状腺所独有的,它是甲状腺消融治疗后甲状腺癌复发或转移的敏感指标。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Andrew N Hoofnagle et al.
Clinical chemistry, 54(11), 1796-1804 (2008-09-20)
Quantification of serum tumor markers plays an important role in determining whether patients treated for cancer require further therapy. Whereas large-scale proteomic efforts aim to identify novel tumor markers to facilitate early detection, optimization of methods for quantifying known tumor
Morgan E Abernathy et al.
NPJ vaccines, 6(1), 126-126 (2021-10-27)
HIV-1 vaccine design aims to develop an immunogen that elicits broadly neutralizing antibodies against a desired epitope, while eliminating responses to off-target regions of HIV-1 Env. We report characterization of Ab1245, an off-target antibody against the Env gp120-gp41 interface, from
Perrine Munier et al.
Annales de biologie clinique, 69(6), 721-725 (2011-11-30)
Thyroglobuline (Tg) is a large molecule of high molecular weight mainly indicated in monitoring differentiated thyroid cancer (DTC), its measurement remains difficult. We report the case of a patient who underwent total thyroidectomy for a poorly differentiated thyroid insular carcinoma.
Akio Yoshida et al.
The Journal of clinical endocrinology and metabolism, 94(2), 442-448 (2008-12-04)
Pendrin is an apical protein of thyroid follicular cells, responsible for the efflux of iodide into the follicular lumen via an iodide-chloride transport mechanism. It is unknown whether pendrin is recognized by autoantibodies. Our objective was to examine the prevalence
Kouame Adou et al.
Analytical chemistry, 81(24), 10186-10192 (2009-11-21)
A charge reduction (CR) interface for electrospray ionization that permits simultaneous analysis of nanoparticle solutions by multiple detection methods was characterized. In the direct infusion configuration, a constant flow of analyte solution undergoes electrospray ionization (ESI). The charged aerosol is

商品

With the emergence of mass spectrometry for the clinical measurement of proteins in biological matrices, the development of biological reference materials will continue to grow in importance.

With the emergence of mass spectrometry for the clinical measurement of proteins in biological matrices, the development of biological reference materials will continue to grow in importance.

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