D6446

DOV 216,303

≥98% (HPLC)

• 别名: (±)-1-(3,4-dichlorophenyl)-3-azabicyclo-[3.1.0]hexane hydrochloride
• 经验公式（希尔记法）: C₁₁H₁₁Cl₂N · HCl
• CAS号: 86215-36-3
• 分子量: 264.58
• MDL號碼: MFCD06407666
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329798827
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: ≥10 mg/mL
• 起源: Merck & Co., Inc., Kenilworth, NJ, U.S.
• 儲存溫度: −20°C
• SMILES 字串: Cl.Clc1ccc(cc1Cl)C23CNCC2C3
• InChI: 1S/C11H11Cl2N.ClH/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11;/h1-3,8,14H,4-6H2;1H
• InChI 密鑰: KAGBHVBIOJBGBD-UHFFFAOYSA-N

说明

生化／生理作用

Triple reuptake inhibitor (TRI); serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI); IC50 values of ~20, 14, and 78 nM, respectively.

特點和優勢

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H319
• 防範說明: P301 + P310 + P330 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Eye Irrit. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable