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Merck

SML2284

Sigma-Aldrich

Mito A iodide

≥98% (HPLC)

别名:

3-(4’-Azidobenzamido)-prop-1-yl]triphenylphosphonium iodide

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About This Item

经验公式(希尔记法):
C28H26IN4OP
分子量:
592.41
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to light brown

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

2-8°C

SMILES 字串

O=C(NCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(N=[N+]=[N-])C=C4.[I-]

生化/生理作用

MitoA is selective hydrogen sulfide (H2S) probe targeting mithchondria suitable for in vivo use. MitoA accumulates in mitochondria within tissues, where it is converted to MitoN by reaction with H2S. Both compounds are detected sensitively by LC-MS/MS.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Sabine Arndt et al.
The Journal of biological chemistry, 292(19), 7761-7773 (2017-03-23)
Hydrogen sulfide (H2S) is produced endogenously in vivo and has multiple effects on signaling pathways and cell function. Mitochondria can be both an H2S source and sink, and many of the biological effects of H2S relate to its interactions with

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