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Merck

V7264

Sigma-Aldrich

文拉法辛 盐酸盐

≥98% (HPLC), powder

别名:

(+/-)-1-[2-(二甲基氨基)-1-(4-甲氧基苯基)乙基]环己醇盐酸盐, 盐酸文拉法辛

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About This Item

经验公式(希尔记法):
C17H27NO2 · HCl
CAS号:
分子量:
313.86
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated
protect from light

顏色

white

溶解度

H2O: >10 mg/mL

起源

Wyeth

SMILES 字串

Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2

InChI

1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H

InChI 密鑰

QYRYFNHXARDNFZ-UHFFFAOYSA-N

基因資訊

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生化/生理作用

文拉法辛是抗抑郁药。文拉法辛在人中的抗抑郁作用机制与其在中枢神经系统中神经递质活性的增强有关。文拉法辛是神经元 5-羟色胺和去甲肾上腺素再摄取的有效抑制剂,是多巴胺再摄取的弱抑制剂。在体外,文拉法辛对毒蕈碱、组胺能或 α-1 肾上腺素能受体无明显活性。文拉法辛不具有 MAO 抑制剂活性。

特點和優勢

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Environment

危險聲明

防範說明

危險分類

Aquatic Chronic 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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