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化驗
97.0-103.0% (HPLC)
形狀
powder
mp
49-51 °C (lit.)
儲存溫度
2-8°C
SMILES 字串
[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
InChI
1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
InChI 密鑰
PWOQRKCAHTVFLB-UHFFFAOYSA-N
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應用
环磷酰胺是氮芥类烷化剂，被广泛用于抗肿瘤和抗免疫药物的作用机理研究。
生化／生理作用
环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。
包裝
包装在 100 mL 血清瓶中，具有硅/PTFE 隔膜和铝封。
注意
将相容溶剂直接注入小瓶中，可制备任何所需规格的溶液，无需暴露。
重構
将内容物溶于 100 mL 溶剂中，得到 1% 溶液。
法律資訊
Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany
ISOPAC
产品编号
说明
价格
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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We presents an article on ABC Transporters and Cancer Drug Resistance
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