BP1094

环磷酰胺

British Pharmacopoeia (BP) Reference Standard

• 别名: 环磷酰胺 一水合物, 2-[双(2-氯乙基)氨基]四氢-2H-1,3,2-噁磷-2-氧化物, Cytoxan
• 经验公式（希尔记法）: C₇H₁₅Cl₂N₂O₂P · H₂O
• CAS号: 6055-19-2
• 分子量: 279.10
• Beilstein: 4678992
• MDL號碼: MFCD00149395
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: cyclophosphamide
• 形狀: crystalline
• 儲存期限: limited shelf life, expiry date on the label
• 製造商／商標名: BP
• mp: 49-51 °C (lit.)
• 應用: pharmaceutical; pharmaceutical small molecule
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• InChI 密鑰: PWOQRKCAHTVFLB-UHFFFAOYSA-N

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Cyclophosphamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Cyclophosphamide Oral Solution

生化／生理作用

环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。

包裝

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H301,H340,H350,H360FD
• 防範說明: P202 - P264 - P270 - P280 - P301 + P310 - P405
• 危險分類: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 235.4 °F - closed cup
• 閃點（°C）: 113 °C - closed cup