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Merck

C5423

Sigma-Aldrich

克仑特罗 盐酸盐

≥95% (TLC), powder, β2-adrenoceptor agonist

别名:

4-氨基-& # 945;-(叔丁基氨基甲基)-3,5-二氯苄醇 盐酸盐

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About This Item

经验公式(希尔记法):
C12H18Cl2N2O · HCl
CAS号:
分子量:
313.65
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

product name

克仑特罗 盐酸盐, ≥95%

品質等級

化驗

≥95%

形狀

powder

drug control

Home Office Schedule 4.2

儲存溫度

2-8°C

SMILES 字串

Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1

InChI

1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H

InChI 密鑰

OPXKTCUYRHXSBK-UHFFFAOYSA-N

基因資訊

human ... ADRB2(154)

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應用

盐酸克伦特罗已被用作:
  • 来自鸡骨骼肌的 β-肾上腺素能受体(β -AR)的激动剂,以诱导大鼠
  • 的咬肌、二腹肌和颞肌中的肥大效应。
  • 作为串联质谱(MS-MS)中的参照β-激动剂标准

生化/生理作用

盐酸克伦特罗是一种& # 946;2-肾上腺素受体激动剂和支气管扩张剂。它能有效改善哮喘患者的呼气峰流速(PEFR)。克伦特罗也是一种提高性能的药物,因为它刺激中枢神经系统并改善氧转运。克伦特罗在扩张型心肌病患者中引发心脏保护功能。

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Carc. 2 - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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C A Izeboud et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 48(9), 497-502 (1999-10-16)
To investigate the suppressive effects of the beta-agonist clenbuterol on the release of TNF-alpha and IL-6 in a lipopolysaccharide (LPS)-model of inflammation, both in vitro and in vivo. Human U-937 cell line (monocyte-derived macrophages), and male Wistar rats (200-250 g).
Jelka Pleadin et al.
Meat science, 86(3), 733-737 (2010-07-30)
The aim of this study was to determine the level of clenbuterol residues in muscle tissue of pigs after repeat administration in a growth-promoting dose. An anabolic dose of clenbuterol (20 μg/kg body mass per day) was administered orally to
I Semkova et al.
Brain research. Brain research reviews, 30(2), 176-188 (1999-10-19)
Neurotrophins and other neurotrophic factors have been shown to support the survival and differentiation of many neuronal populations of the central and peripheral nervous system. Therefore, administering neurotrophic factors could represent an alternative strategy for the treatment of acute and
Structural characterization of a new form of clenbuterol, a well-known decongestant and bronchodilator also used as a performance-enhancing drug
Toro R, et al.
Powder Diffraction, 28(2), 63-67 (2013)
A trial of clenbuterol in bronchial asthma.
Anderson G and Wilkins E
Thorax, 32(6), 717-719 (1977)

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