推荐产品
品質等級
無菌
γ-irradiated
種類
Type IV-S
產品線
BioReagent
形狀
lyophilized powder
技術
cell culture | mammalian: suitable
雜質
salt, essentially free
溶解度
PBS: 5 mg/mL, slightly hazy
H2O: soluble, slightly hazy
儲存溫度
−20°C
正在寻找类似产品? 访问 产品对比指南
應用
来自洋刀豆(刀豆)的伴刀豆球蛋白A已用于以下情形:
- 诱导脾胚芽生殖
- 从B6和lpr脾细胞生成ConA blast靶标
- 刺激雌激素和安慰剂治疗小鼠的脾淋巴细胞
生化/生理作用
刀豆素 A 无血型特异性,但对末端 α-D-甘露糖基和 α-D-葡糖基残基具有亲和力。需要 Ca2+ 和 Mn2+ 离子存在才能显示活性。刀豆素 A 在 pH 6.5 或更低的条件下解离为二聚体。pH 在 5.8 至 7.0 之间时,刀豆素 A 以四聚体形式存在;pH 高于 7.0 时,形成更高的聚合体。根据聚合程度不同,刀豆素 A 可能显示出具有促有丝分裂的活性。琥珀酰化可以生成一种能够在 pH 高于 5.6 时仍保持二聚体形式的活性二聚体。
分析報告
据报道,凝集活性以μg/ml表示,并且在Ca2+ 和Mn2+ 浓度为1 mg/ml、pH 6.8的磷酸缓冲盐溶液中进行连续稀释测定。该活性是在25°C下孵育1小时的2%人红细胞悬浮液可以凝集的最低浓度。
訊號詞
Danger
危險聲明
危險分類
Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
Frontiers in immunology, 12, 683631-683631 (2021-08-10)
Gene editing of primary T cells is a difficult task. However, it is important for research and especially for clinical T-cell transfers. CRISPR/Cas9 is the most powerful gene-editing technique. It has to be applied to cells by either retroviral transduction
Toxicology letters, 311, 49-57 (2019-04-25)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), the most toxic congener of dioxins, is a persistent and ubiquitous environmental contaminant. Although the immunotoxic effects of TCDD have been reported, the mechanisms underlying these effects are still unclear. In this study, we have determined the toxic
CD8+ T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function
The Journal of Experimental Medicine, 195(11), 1407-1418 (2002)
Toxicology letters, 311, 49-57 (2019-04-25)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), the most toxic congener of dioxins, is a persistent and ubiquitous environmental contaminant. Although the immunotoxic effects of TCDD have been reported, the mechanisms underlying these effects are still unclear. In this study, we have determined the toxic
Immune responsiveness of splenocytes after chronic daily melatonin administration in male Syrian hamsters
Immunology Letters, 58(2), 95-100 (1997)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门