所有图片(2)
About This Item
经验公式（希尔记法）:
C18H29NO3 · HCl
CAS号:
分子量:
343.89
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
化驗
>98% (HPLC)
形狀
solid
儲存條件
desiccated
顏色
white
溶解度
H2O: soluble 36 mg/mL
起源
Alcon
SMILES 字串
Cl[H].CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1
InChI
1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
InChI 密鑰
CHDPSNLJFOQTRK-UHFFFAOYSA-N
基因資訊
human ... ADRB1(153)
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應用
Betaxolol hydrochloride has been used as a β1 blocking agent:
- for the preparation of crystals of (R,S)-betaxolol (BE-IV).
- to treat mammalian cells prior cell stimulation experiments.
- to study the solid structure of metoprolol.
生化／生理作用
Betaxolol hydrochloride has the ability to block calcium channels. Betaxolol is a selective β1 adrenoreceptor antagonist. It has neuroprotective effects on retinal neurons.
特點和優勢
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Alcon. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
The solid-state structure of the beta-blocker metoprolol: a combined experimental and in silico investigation
Rossi P, et al.
Acta Crystallographica Section C, Structural Chemistry, 75(2) (2019)
I A Latfullin et al.
Klinicheskaia meditsina, 88(2), 68-71 (2010-11-26)
The use of beta-blockers is an important component of therapy of cardiovascular pathology (e.g. coronary heart disease, arterial hypertension) in menopausal women. Comparative data on the efficiency of lokren and carvedilol for the correction of grade 2 AH are presented.
Josine van der Schoot et al.
Ophthalmology, 117(1), 30-34 (2009-11-10)
Short-wavelength automated perimetry (SWAP) has been claimed to predict conversion to glaucoma 3 to 4 years before standard automated perimetry (SAP) defects occur. This study compared the moment of glaucomatous conversion between SWAP and SAP. Prospective, longitudinal follow-up study. Four
Intraocular pressure reduction with a fixed treatment protocol in the Early Manifest Glaucoma Trial.
Anders Heijl et al.
Acta ophthalmologica, 89(8), 749-754 (2010-03-20)
To evaluate: (i) the relationship between intraocular pressure (IOP) reduction attained with a fixed treatment protocol and the untreated IOP level; (ii) the consistency of IOP reduction over time; and (iii) whether there is a threshold pretreatment IOP level below
Allergic contact dermatitis due to the beta-blocker betaxolol in eyedrops, with cross-sensitivity to timolol.
Massimiliano Nino et al.
Contact dermatitis, 62(5), 319-320 (2010-06-12)
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