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Key Documents

A8556

Sigma-Aldrich

6′-唾液酸乳糖 钠盐

from bovine milk or colostrum, ≥97% (HPLC)

别名:

α-NeuNAc-(2→6)-β-D-Gal-(1→4)-D-Glc, 6′-N-乙酰神经氨酸-乳糖 钠盐, 6′-SL

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About This Item

线性分子式:
C23H38NO19Na
CAS号:
分子量:
655.53
分類程式碼代碼:
12352201
NACRES:
NA.25

生物源

bovine milk or colostrum

品質等級

化驗

≥97% (HPLC)

形狀

powder

雜質

≤1% free N-Acetyl Neuraminic Acid
≤11% water (Karl Fischer)

顏色

white to off-white

溶解度

water: 20 mg/mL, clear, colorless

正離子痕跡

Na: 2.6-4.5% (anhydrous)

儲存溫度

−20°C

SMILES 字串

[Na+].[H][C@]1(O[C@](C[C@H](O)[C@H]1NC(C)=O)(OC[C@H]2OC(O)[C@H](O)[C@@H](O)[C@@H]2O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)C([O-])=O)[C@H](O)[C@H](O)CO

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應用

6'-唾液酸乳糖是一种化合物,其中乙酰神经氨酸 (NANA) 单元在 6 位与乳糖的半乳糖基单元连接。在 3'-唾液酸乳糖中,该连接位于 3 位。3'-唾液酸乳糖和 6′-唾液酸乳糖用于区分和表征病毒的结合域,如流感病毒和鼻炎病毒,它们识别 NANA 封端细胞表面受体。3'-唾液酸乳糖和 6'-唾液酸乳糖用作分析方法中的引用化合物,用于测定乳汁和初乳等物质中是否存在唾液酸乳糖。

其他說明

为了全面了解我们针对客户研究提供的各种寡糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Ousman Jobe et al.
Journal of leukocyte biology, 99(6), 1089-1106 (2015-12-17)
Monocytes and monocyte-derived macrophages express relatively low levels of CD4. Despite this, macrophages can be effectively infected with human immunodeficiency virus type 1. Macrophages have a critical role in human immunodeficiency virus type 1 transmission; however, the mechanism or mechanisms
Maria Elena Ortiz-Soto et al.
PloS one, 11(5), e0155410-e0155410 (2016-05-12)
Sialyltransferases (STs) are disulfide-containing, type II transmembrane glycoproteins that catalyze the transfer of sialic acid to proteins and lipids and participate in the synthesis of the core structure oligosaccharides of human milk. Sialic acids are found at the outermost position
Rit Bahadur Gurung et al.
Regulatory toxicology and pharmacology : RTP, 95, 182-189 (2018-03-21)
We performed a series of toxicity studies on the safety of 6'-sialyllactose (6'-SL) sodium salt as a food ingredient. 6'-SL sodium salt, up to a maximum dose of 5000 μg/plate, did not increase the number of revertant colonies in five
Shuang-Xi Chen et al.
Neural regeneration research, 15(6), 1058-1065 (2019-12-12)
Oxidative stress contributes to the pathogenesis of neurodegenerative diseases. With the aim to find reagents that reduce oxidative stress, a phage display library was screened for peptides mimicking α2,6-sialyllactose (6'-SL), which is known to beneficially influence neural functions. Using Sambucus
Randall C Robinson et al.
PloS one, 13(4), e0196513-e0196513 (2018-04-27)
Milk oligosaccharides (OS) are a key factor that influences the infant gut microbial composition, and their importance in promoting healthy infant development and disease prevention is becoming increasingly apparent. Investigating the structures, properties, and sources of these compounds requires a

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