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Merck

A4626

Sigma-Aldrich

1-乙酰基-2-苯肼

≥98%

别名:

N-Acetyl-N′-phenylhydrazine, acetylphenylhydrazine

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About This Item

线性分子式:
CH3CONHNHC6H5
CAS号:
分子量:
150.18
EC號碼:
MDL號碼:
分類程式碼代碼:
12352127
PubChem物質ID:
NACRES:
NA.25

品質等級

化驗

≥98%

形狀

(Powder with Chunk(s) or Crystals with Chunk(s))

mp

128-131 °C (lit.)

SMILES 字串

CC(=O)NNc1ccccc1

InChI

1S/C8H10N2O/c1-7(11)9-10-8-5-3-2-4-6-8/h2-6,10H,1H3,(H,9,11)

InChI 密鑰

UICBCXONCUFSOI-UHFFFAOYSA-N

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應用

用于造血系统研究的 1-乙酰基-2-苯肼 (AcPhHZ) 可与氧合血红蛋白反应形成自由基,可用于诱导溶血性贫血。

生化/生理作用

乙酰苯肼(1-Acetyl-2-phenylhydrazine,AcPhHZ) 是一种用于实验动物模型的血管肿瘤引发剂。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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R S Weinstein et al.
Journal of cell science, 94 ( Pt 3), 593-600 (1989-11-01)
An unusual form of red cells (called sequestrocytes) that circulate in the peripheral blood of patients with sickle cell anemia has been identified. In wetmount light microscopy preparations, sequestrocytes appear as massively vacuolated erythrocytes. We have shown by transmission electron
P Caprari et al.
Biochemical medicine and metabolic biology, 45(1), 16-27 (1991-02-01)
After in vitro treatment of normal, glucose-6-phosphate dehydrogenase-deficient or pyruvate kinase-deficient human erythrocytes with three different oxidizing agents, the extent of lipid peroxidative degradation and the alterations of membrane proteins were evaluated. Exposure to tert-butylhydroperoxide induced, most markedly in G6PD-
I Goto et al.
American journal of veterinary research, 54(4), 622-626 (1993-04-01)
To clarify the oxidant defense functions of reduced glutathione (GSH) in erythrocytes, the effect of GSH deficiency on in vitro oxidant defense was studied, using GSH-deficient sheep erythrocytes (low-GSH cells). The formation of Heinz bodies in low-GSH cells was higher
S Croci et al.
Biochimica et biophysica acta, 1568(1), 99-104 (2001-12-04)
The oxidative action of acetylphenylhydrazine (APH) on red blood cells obtained from healthy donors and from patients with breast cancer has been investigated by Mössbauer spectroscopy. Whole blood was incubated with APH for different time periods and the Mössbauer spectra
Min Zhu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2543-2547 (2012-01-20)
To investigate Siwu decoction and its composite drugs on the blood-deficiency model mice induced by acetylphenyhydrazine and cyclophosphamide. Acetylphenyhydrazine and cyclophosphamide were used to copy the blood-deficiency model mice. Automatic hematology analyzer was used to test the peripheral hemogram. Weighting

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