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Key Documents

42867

Sigma-Aldrich

硫酸葡聚糖 钠盐

Mr ~40,000

别名:

DSS Dextran Sulfate Sodium

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.25

形狀

powder

品質等級

100

分子量

Mr ~40,000

損耗

≤10% loss on drying

顏色

white to off-white

有用的pH值範圍

6.0-8 (10 g/L)

mp

(Decomposes on heating.)

溶解度

water: soluble

儲存溫度

room temp

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相关类别

一般說明

右旋糖酐是一种无水葡萄糖的聚合物。 由大约95%的α-D-(166)键组成。 其它（163）链接组成了葡聚糖的支链。

應用

硫酸葡聚糖通常用于选择性沉淀脂蛋白，探针杂交膜固定DNA，从DNA-组蛋白复合物中释放DNA，以及抑制RNA与核糖体结合。

生化／生理作用

葡聚糖硫酸钠通过与结肠中链脂肪酸结合并诱导炎症，在小鼠和大鼠体内引发结肠炎。

其他說明

为了全面了解我们针对客户研究提供的各种葡聚糖产品，建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Li Cao et al.
International immunopharmacology, 72, 264-274 (2019-04-21)
Extracellular vesicles (EVs) secreted by bone marrow mesenchymal stem cells (BMSCs) have shown repairing effects in tissue damage. However, their efficacy and mechanism in the treatment of ulcerative colitis (UC), a type of chronic inflammatory bowel disease, are unclear. To
Andrey V Markov et al.
Molecules (Basel, Switzerland), 25(10) (2020-05-28)
Semi-synthetic triterpenoids, bearing cyano enone functionality in ring A, are considered to be novel promising therapeutic agents with complex inhibitory effects on tissue damage, inflammation and tumor growth. Previously, we showed that the cyano enone-containing 18βH-glycyrrhetinic acid derivative soloxolone methyl
Hamed Laroui et al.
PloS one, 7(3), e32084-e32084 (2012-03-20)
Inflammatory bowel diseases (IBDs), primarily ulcerative colitis and Crohn's disease, are inflammatory disorders caused by multiple factors. Research on IBD has often used the dextran sodium sulfate (DSS)-induced colitis mouse model. DSS induces in vivo but not in vitro intestinal
N Facchinello et al.
Scientific reports, 7(1), 4371-4371 (2017-07-01)
Glucocorticoids (GCs) play important roles in developmental and physiological processes through the transcriptional activity of their cognate receptor (Gr). Using CRISPR/Cas9 technology, we established a zebrafish null Gr mutant line and compared its phenotypes with wild type and a zebrafish
Maike M K Hansen et al.
Cell, 173(7), 1609-1621 (2018-05-15)
Diverse biological systems utilize fluctuations ("noise") in gene expression to drive lineage-commitment decisions. However, once a commitment is made, noise becomes detrimental to reliable function, and the mechanisms enabling post-commitment noise suppression are unclear. Here, we find that architectural constraints
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