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生物源
bacterial (Leuconostoc mesenteroides)
品質等級
形狀
powder
光學活性
[α]/D 90 to 105 °, c = 6% (w/v)
分子量
average mol wt 9,000-20,000
成份
Sulfur Content, 16.0-19.0%
顏色
white to off-white
有用的pH值範圍
5.5 - 8.0
溶解度
H2O: 100 mg/mL
儲存溫度
room temp
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一般說明
葡聚糖硫酸钠是α-1,6-D-吡喃葡萄糖的天然聚合物。它是一种亲水性、可生物降解和生物相容性的聚阴离子聚合物。这种高度分枝的多糖具有1,6和1,4糖苷键,每个糖基单位由2.3个硫酸盐基组成。
應用
来自明串珠菌属的右旋糖酐硫酸钠已用于:
- 评价硫酸盐聚糖参与重组人前顶蛋白/顶蛋白与透明带(ZP)糖蛋白相互作用
- 将胚胎第5天的小鸡胚胎注射入玻璃体腔,以评估眼睛大小,并研究其对视网膜细胞增殖的影响
- 检测TNF-刺激基因6(TSG-6)与固定化透明质酸(HA)结合的结构特异性
生化/生理作用
硫酸右旋糖酐可能具有抗凝血和抗病毒的特性。它还有助于降低胆固醇水平。在医疗领域广泛用作血浆体积膨胀剂和纤溶剂。硫酸右旋糖酐也可用作壳聚糖的交联剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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实验方案
Dextran sulfates are supplied as the sodium salt forms, making them soluble and stable in water. Dextran sulfate contains approximately 17% sulfur which is equivalent to approximately 2.3 sulfate groups per glucosyl residue.
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