27029

胆酸钠 水合物

≥97.0% (dried material, NT)

• 别名: 3α,7α,12α-三羟基-5β-胆甾烷-24-羧酸 钠盐, 胆酸 钠盐
• 经验公式（希尔记法）: C₂₄H₃₉NaO₅ · xH₂O
• CAS号: 206986-87-0
• 分子量: 430.55 (anhydrous basis)
• Beilstein: 3582354
• EC號碼: 206-643-5
• MDL號碼: MFCD00150749
• 分類程式碼代碼: 12161900
• PubChem物質ID: 57648188
• NACRES: NA.25

属性

• 描述: anionic
• 品質等級: 200
• 化驗: ≥97.0% (dried material, NT)
• 形狀: powder
• 光學活性: [α]20/D +36±2°, c = 0.6% in ethanol (dry matter)
• 分子量: micellar avg mol wt 900-1300
• 凝集数: 2-3
• 損耗: ≤5% loss on drying
• CMC: 9-15 mM (20-25°C)
• 溶解度: H₂O: 0.1 M; H₂O: 100 mg/mL
• HLB: 18
• SMILES 字串: O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
• InChI 密鑰: MUVVIYFKOVLQHL-RCVKHMDESA-M

说明

一般說明

水合胆酸钠是一种生物表面活性剂，可作为水溶液中的还原剂。

水合胆酸钠是一种非变性阴离子洗涤剂。

應用

• Optimization in Transdermal Drug Delivery: Applied in the formulation of ultra-elastic nanovesicles, sodium cholate hydrate enhances the bioavailability and anti-inflammatory efficacy of deflazacort, demonstrating its potential in transdermal drug delivery systems, which can be adapted for diagnostic purposes (Ali et al., 2021).


• Nanocarrier Formulations for IVDs: The study utilizes sodium cholate hydrate in the surface modification of bilosomes, serving as a functional and biocompatible nanocarrier for hybrid compounds, a method applicable to the formulation of innovative IVD reagents (Waglewska et al., 2020).


• IVD Reagent Formulation for Skin Delivery: Sodium cholate hydrate is featured in the development of nano-transfersomes for the delivery of antioxidants, showcasing its role in creating skin-applied diagnostic reagents that offer antioxidant and anti-aging effects (Avadhani et al., 2017).


• Sorting and Separation Techniques in Nanotechnology: Demonstrating the affinity-mediated sorting order reversal, sodium cholate hydrate is critical in density gradient ultracentrifugation techniques, highlighting its utility in the precise sorting and preparation of materials for diagnostic assays (Jang et al., 2016).

安全信息

• 危險聲明: H412
• 防範說明: P273 - P501
• 危險分類: Aquatic Chronic 3
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)