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Merck

T1850000

维甲酸

European Pharmacopoeia (EP) Reference Standard

别名:

视黄酸, ATRA, 全反式维甲酸, 维生素A酸, 维甲酸

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About This Item

经验公式(希尔记法):
C20H28O2
CAS号:
分子量:
300.44
Beilstein:
2057223
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

生物源

synthetic

等級

pharmaceutical primary standard

agency

EP

API 家族

tretinoin

形狀

solid

製造商/商標名

EDQM

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

180-181 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

CC1=C(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)C(C)(C)CCC1

InChI

1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+

InChI 密鑰

SHGAZHPCJJPHSC-YCNIQYBTSA-N

基因資訊

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一般說明

本品根据现行药典要求提供和指定。所有为支持本产品而提供的信息,包括SDS和任何产品信息小册子,均根据现行药典制定和发布。更多信息和支持请访问药典颁发机构网站。

维甲酸是一种用于治疗各种皮肤病的药物,如光损伤皮肤、痤疮等。它用作抗衰老产品,也用作白血病的口服药物。

應用

本欧洲药典参考标准仅用于欧洲药典中明确规定的用途。

生化/生理作用

全−反式−视黄酸(ATRA)是视黄酸受体(RAR)和视黄醇类 X 受体(RXR)的配体。所结合的RAR和RXR可作为调节正常细胞和恶性细胞的生长和分化的转录因子。细胞色素P450(CYP)可催化ATRA的4-羟基化。视黄酸可使胚胎干细胞成为神经元。

包裝

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他說明

可能适用相应的销售限制。

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - Skin Irrit. 2

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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