PHR1710

盐酸西替利嗪相关化合物A

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: Cetirizine ethyl ester dihydrochloride, (RS)-2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]acetic acid ethyl ester dihydrochloride (Cetirizine hydrochloride Related Compound A), (RS)-2-[2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]acetic acid ethyl ester dihydrochloride
• 经验公式（希尔记法）: C₂₃H₂₉ClN₂O₃ · 2HCl
• CAS号: 246870-46-2
• 分子量: 489.86
• EC號碼: 206-137-4
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to USP 1102930
• API 家族: cetirizine
• CofA: current certificate can be downloaded
• 包裝: pkg of 40 mg
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: -10 to -25°C
• InChI: 1S/C23H29ClN2O3/c1-2-29-22(27)18-28-17-16-25-12-14-26(15-13-25)23(19-6-4-3-5-7-19)20-8-10-21(24)11-9-20/h3-11,23H,2,12-18H2,1H3
• InChI 密鑰: ASHQTVRYHSZGQY-UHFFFAOYSA-N

说明

一般說明

Cetirizine hydrochloride Related Compound A is an impurity of cetirizine hydrochloride. Cetirizine hydrochloride is a second-generation antihistamine compound. It is a major metabolite of hydroxyzine that exhibits high specific affinity for histamine H1 receptor. It is used for the management of allergies, hay fever, angioedema, and urticaria.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Cetirizine hydrochloride has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry and chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA7298 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H302,H410
• 防範說明: P264 - P270 - P273 - P301 + P312 - P391 - P501
• 危險分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable