PHR1076

美托洛尔 (+)-酒石酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: (±)1-(异丙氨基)-3-[p-(β-甲氧基乙基)苯氧基] -2-丙醇 (+)-酒石酸盐, Lopressor
• 线性分子式: (C₁₅H₂₅NO₃)₂ · C₄H₆O₆
• CAS号: 56392-17-7
• 分子量: 684.81
• EC號碼: 260-148-9
• MDL號碼: MFCD00056257
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823099
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 540; traceable to Ph. Eur. M1830000; traceable to USP 1441301
• API 家族: metoprolol
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: forensics and toxicology; pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2
• InChI: 1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1
• InChI 密鑰: YGULWPYYGQCFMP-CEAXSRTFSA-N
• 基因資訊: human ... ADRB1(153)

说明

一般說明

Metoprolol Tartrate is a β-blocking drug, showing antihypertensive and anti-ischemic effects. It is widely used in the treatment of hypertension and helps in controlling ventricular response in patients with atrial fibrillation.

應用

Metoprolol Tartrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using densitometric technique and spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA6905 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS08,GHS09
• 訊號詞: Warning
• 危險聲明: H361d,H411
• 防範說明: P202 - P273 - P280 - P308 + P313 - P391 - P405
• 危險分類: Aquatic Chronic 2 - Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable