跳转至内容
Merck

PHR1034

Supelco

利多卡因

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

2-二乙氨基-N-(2,6-二甲苯基)乙酰胺, 利多卡因, 赛洛卡因

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C14H22N2O
CAS号:
分子量:
234.34
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to BP 727
traceable to Ph. Eur. L0595000
traceable to USP 1366002

API 家族

lidocaine

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

格式

neat

儲存溫度

2-30°C

SMILES 字串

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChI 密鑰

NNJVILVZKWQKPM-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

一般說明

利多卡因是一种可治疗心律失常的潜在候选药物。
用于质量控制应用的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
利多卡因是一种局部麻醉药,具有明显的抗心律失常和抗惊厥作用。它是中枢神经系统抑制剂,具有镇静、止痛和抗惊厥作用。
用于质量控制的制药二级标准品,为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

應用

利多卡因可作为内参,使用气相色谱(GLC)测定人血清样品中的哌可昔林。
利多卡因可用作药物参考标准品,用于通过色谱技术测定药物制剂中的分析物。
这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

生化/生理作用

Na+通道阻滞剂;在肠胃外给药后可迅速被吸收的IB类抗心律失常药。

分析報告

这些二级标准品可追溯至USP、EP(PhEur)和BP一级标准品。

其他說明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

腳註

要查看该材料的分析证书示例,请在下面的栏位中输入LRAC0142。这只是一个示例证书,可能不是您收到的批次。

推薦產品

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析(使用数字化外标)。可查看该物质的NMR谱图,只需点击几次鼠标,就能进行在线样品比对。欢迎点击了解更多,开启免费试用之旅。

相關產品

产品编号
说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Simultaneous determination of tolperisone and lidocaine by high performance liquid chromatography
Liawruangrath S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 26(5-6), 865-872 (2001)
Stability indicating HPLC method for the estimation of oxycodone and lidocaine in rectal gel
Gebauer MG, et al.
International Journal of Pharmaceutics, 223(1-2), 49-54 (2001)
A rapid method for the determination of perhexiline in serum using gas-liquid chromatography
CooperHDJ and Turnell CD
Annals of Clinical Biochemistry, 17, 155-158 (1980)
High-performance liquid chromatographic method for the simultaneous determination of lidocaine and its N-dealkylated metabolites in plasma
Nation.LR, et al.
Journal of Chromatography. B, Biomedical Applications, 162, 466-473 (1979)
Development and validation of RP-HPLC method for cetrimonium bromide and lidocaine determination.
Malenovic A, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 60(2), 157-161 (2005)

商品

Separation of Lidocaine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; Amiodarone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; (±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; N-Desethylamiodarone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

The benefit of HILIC over traditional reversed-phase chromatography is two-fold for both sample introduction and analyte detection. First, the high acetonitrile concentration of HILIC mobile phases allows for direct analysis of precipitated plasma samples without the need for additional sample solvent exchange. Second, the high acetonitrile content provides increased analyte response in positive ESI MS detection.

相关内容

HILIC mobile phases consist of a high composition of acetonitrile, which facilitates the direct analysis of precipitated plasma samples without the need for additional sample solvent exchange.

Separation of Amiodarone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; N-Desethylamiodarone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Lidocaine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; (±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门