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Merck
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C8037

Supelco

丙酸氯倍他索

analytical standard

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About This Item

经验公式（希尔记法）:
C25H32ClFO5
CAS号:
25122-46-7
分子量:
466.97
EC號碼:
246-634-3
MDL號碼:
MFCD00058499
分類程式碼代碼:
41116107
PubChem物質ID:
329775158
NACRES:
NA.24

等級

analytical standard

品質等級

200

化驗

≥98%

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
veterinary

形式

neat

儲存溫度

2-8°C

SMILES 字串

CCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)CCl

InChI

1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1

InChI 密鑰

CBGUOGMQLZIXBE-XGQKBEPLSA-N

基因資訊

human ... NR3C1(2908)
rat ... Nr3c1(24413)

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相关类别

一般說明

Clobetasol propionate is a novel and highly potent, topical corticosteroid, which is being assessed for its utility in the treatment of bullous pemphigoid.

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H360Df,H373,H413

危險分類

Aquatic Chronic 4 - Repr. 1B - STOT RE 2

標靶器官

Adrenal gland,Immune system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 2

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCG2396
SLBM1905V
SLBL9280V
SLBD3909V

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Treatment of bullous pemphigoid with topical clobetasol propionate
Westerhof W
Journal of the American Academy of Dermatology, 20, 458-461 (1989)
Open preliminary clinical trial of clobetasol propionate ointment in adhesive paste for treatment of chronic oral vesiculoerosive diseases.
Lozada-Nur F and Huang M Z
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 71(3), 283-287 (1991)
Open preliminary clinical trial of clobetasol propionate ointment in adhesive paste for treatment of chronic oral vesiculoerosive diseases
Lozada-Nur F, et al.
Oral Surgery, Oral Medicine, and Oral Pathology, 71, 283-287 (1991)
Treatment of bullous pemphigoid with topical clobetasol propionate.
Westerhof W.
Journal of the American Academy of Dermatology, 20(3), 458-461 (1989)
M Hofmann et al.
Archives of dermatological research, 305(3), 215-221 (2012-12-18)
Currently, there are no accurate and simple methods available to measure this risk of atrophy in patients treated with topical glucocorticosteroids. In the present clinical trial, we validated a new score (Dermaphot(®) score) to assess the atrophogenic potential of glucocorticosteroids.
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