PHR1398

倍他米松

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 倍他米松, 9α-氟-11β,17α,21-三羟基-16β-甲基孕甾-1,4-二烯-3,20-二酮, 9α-氟-16β-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮, 9α-氟-16β-甲基泼尼松龙
• 经验公式（希尔记法）: C₂₂H₂₉FO₅
• CAS号: 378-44-9
• 分子量: 392.46
• EC號碼: 206-825-4
• MDL號碼: MFCD00062969
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823372

属性

• 生物源: synthetic
• 品質等級: 300
• 等級: certified reference material; pharmaceutical secondary standard
• agency: BP; EP; USP; traceable to BP 575; traceable to Ph. Eur. B1000000; traceable to USP 1066009
• 蒸汽壓力: <0.0000001 kPa ( 25 °C)
• API 家族: betamethasone
• CofA: current certificate can be downloaded
• 包裝: pkg of 1 g
• 儲存條件: protect from light (20 mm aluminium crimp seal for unused portion)
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 顏色: white to light yellow
• mp: 235-237 °C (lit.)
• 溶解度: acetone: sparingly soluble; chloroform: very slightly soluble; ethanol: sparingly soluble; ether: very slightly soluble; methanol: sparingly soluble; water: insoluble
• 密度: 0.305 g/cm³ at 25 °C (77°F)
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 運輸包裝: ambient
• 儲存溫度: 2-30°C
• SMILES 字串: [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• InChI 密鑰: UREBDLICKHMUKA-DVTGEIKXSA-N
• 基因資訊: human ... NR3C1(2908)

说明

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Betamethasone belongs to the corticosteriod family of active pharmaceutical ingredients (APIs). It exhibits anti-inflammatory activity and hence is used in the manufacture of various finished pharmaceutical products and is also employed as a starting material to manufacture other APIs that are related to this steroid family.

應用

Betamethasone may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations by using micellar liquid chromatography technique and reversed-phase high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA2174 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H360FD - H373
• 防範說明: P202 - P260 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 1B - STOT RE 2
• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable