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Merck

34039

Supelco

麻保沙星

VETRANAL®, analytical standard

别名:

9-氟代-2,3-二氢-3-甲基-10-(4-甲基-哌嗪)-7-氧代-7H-吡啶并[1,2,3-ij][1,2,4]苯并噁二嗪-6-羧酸, Zeniquin®

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About This Item

经验公式(希尔记法):
C17H19FN4O4
分子量:
362.36
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES 字串

CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4N(C)COc2c34)C(O)=O

InChI

1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)

InChI 密鑰

BPFYOAJNDMUVBL-UHFFFAOYSA-N

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一般說明

Marbofloxacin belongs to the group of synthetic fluoroquinolone compounds, widely used as a veterinary anti-bacterial drug. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria.

應用

The analytical standard can be used as follows:
  • Surface-enhanced Raman spectroscopy-based determination of marbofloxacin in chicken and duck samples using β-cyclodextrin-modified silver nanoparticles (β-CD-AgNPs)
  • Analysis of synovial fluid and plasma samples obtained from dairy cows for marbofloxacin by high-performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS/MS) following ultrafiltration of the samples
  • Development of an indirect competitive ELISA (icELISA) method for the combined analysis of marbofloxacin and ofloxacin in raw milk and porcine samples
  • Multi-residue analysis of oxolinic acid, flumequine, marbofloxacin, and enrofloxacin in commercial honey samples by micellar liquid chromatography coupled with fluorescence detection
  • Simultaneous determination of marbofloxacin and trovafloxacin in sheep plasma samples by HPLC combined with UV detection
  • Quantification of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.

其他說明

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Zeniquin is a registered trademark of Pfizer, Inc.

危險聲明

防範說明

危險分類

Aquatic Chronic 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

個人防護裝備

Gloves


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分析证书(COA)

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Blood concentrations of marbofloxacin and its in vivo effect in yellow-bellied slider turtles (Trachemys scripta scripta) after a single intracoelomic injection at 3 dose rates.
Vercelli C, et al.
Journal of Exotic Pet Medicine, 25(4), 295-304 (2016)
Determination of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.
Garcia M A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 729(1-2), 157-161 (1999)
C Vilalta et al.
Journal of veterinary pharmacology and therapeutics, 37(6), 542-549 (2014-06-07)
This study evaluated the theoretical clinical outcome of three marbofloxacin posology regimens in two groups of pigs (weaners and fatteners) for the treatment of Actinobacillus pleuropneumoniae (App) and Haemophilus parasuis (Hp) infection and the appearance of resistant bacteria due to
Xiaoqiang Liu et al.
Veterinary microbiology, 174(3-4), 514-522 (2014-12-04)
This study explored and compared the mechanisms and selective concentration of resistance between a 3rd (pradofloxacin) and 2nd (ciprofloxacin) generation fluoroquinolone. Pradofloxacin- and ciprofloxacin-resistant mutants were selected by stepwise exposure of Escherichia coli (E. coli) to escalating concentrations of pradofloxacin
Seung Ryul Han et al.
Biochemical and biophysical research communications, 448(4), 397-402 (2014-05-06)
Danofloxacin is a synthetic fluoroquinolone with broad spectrum antibacterial activity that is used for the treatment of respiratory diseases in animal husbandry. However, danofloxacin has many adverse reactions and is toxic to humans. Especially, it detrimentally affects muscle, central nerve

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