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Merck
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33864

Supelco

替米可新

VETRANAL®, analytical standard, mix of isomers

别名:

20-脱氧-20-(3,5-二甲基-1-呱啶基)脱红霉糖泰乐菌素

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About This Item

经验公式（希尔记法）:
C46H80N2O13
分子量:
869.13
MDL號碼:
MFCD19705582
分類程式碼代碼:
41116107
PubChem物質ID:
329754677
NACRES:
NA.24

等級

analytical standard

品質等級

100

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

CC1OC(OCC(C(CC)O2)/C=C(/C=C/C(C(C)CC(CCN3CC(C)CC(C)C3)C(OC4OC(C)C(O)C(N(C)C)C4O)C(C)C(O)CC2=O)=O)C)C(OC)C(OC)C1O

InChI

1S/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1

InChI 密鑰

JTSDBFGMPLKDCD-XVFHVFLVSA-N

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相关类别

一般說明

Tilmicosin is a semisynthetic macrolide antibiotic, with broad spectrum activity towards Mycoplasma spp., Pasteurella spp., and various gram-positive organisms in animals.

應用

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tilmicosin may be used as a reference standard for the determination of the analyte in chicken, swine, cattle, sheep tissues and milk samples using liquid chromatography with ultraviolet detection (LC-UV).

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Warning

危險聲明

H302,H373,H410

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

標靶器官

Cardio-vascular system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

個人防護裝備

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCG2736
BCCD7299
BCCB4507
BCBV4513
BCBT8086

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P Bosi et al.
Journal of animal science, 89(12), 4043-4053 (2011-07-05)
The aim of this study was to determine the effects of 3 antibiotics used for pulmonary pathologies added in the feed of weaned pigs on growth performance, commensal microbiota, and immune response. At weaning, a total of 72 pigs were
David G McClary et al.
Journal of the American Veterinary Medical Association, 239(1), 129-135 (2011-07-02)
To determine associations between in vitro minimum inhibitory concentrations (MICs) of tilmicosin against Mannheimia haemolytica and Pasteurella multocida and in vivo tilmicosin treatment outcome among calves with clinical signs of bovine respiratory disease (BRD). Observational, retrospective, cohort study. 976 feeder
Michael D Apley et al.
Foodborne pathogens and disease, 9(3), 272-279 (2012-02-14)
When considering the development of antimicrobial resistance in food animals, comparing gross use estimates of different antimicrobials is of little value due to differences in potencies, duration of activity, relative effect on target and commensal bacteria, and mechanisms of resistance.
F J Reynaldi et al.
Revista Argentina de microbiologia, 42(4), 279-283 (2011-01-14)
American Foulbrood (AFB) caused by the spore-forming bacterium Paenibacillus larvae is the most serious disease of bacterial origin affecting larvae and pupae of honeybees. Antibiotics are used in many countries for the control of AFB in high incidence areas, but
Yingyu Liu et al.
Microbial drug resistance (Larchmont, N.Y.), 18(6), 604-615 (2012-09-01)
The Haemophilus parasuis respiratory tract pathogen poses a severe threat to the swine industry despite available antimicrobial therapies. To gain a more detailed understanding of the molecular mechanisms underlying H. parasuis response to tilmicosin treatment, microarray technology was applied to
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