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Merck

29992

Sigma-Aldrich

DL-α-生育酚乙酸酯

tested according to Ph. Eur.

别名:

生育酚乙酸酯, 维生素 E 醋酸酯

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About This Item

经验公式(希尔记法):
C31H52O3
CAS号:
分子量:
472.74
Beilstein:
97512
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

生物源

synthetic

品質等級

agency

USP/NF
tested according to Ph. Eur.

化驗

96.5-102.0%

形狀

liquid

密度

0.96 g/mL at 20 °C (lit.)

應用

cell analysis
pharmaceutical (small molecule)

儲存溫度

2-8°C

SMILES 字串

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI 密鑰

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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一般說明

α-生育酚是一种维生素E。维生素E可以从膳食来源获取。RRR‐α‐生育酚是α-生育酚的天然形式。

應用

DL-α-生育酚乙酸酯可作为维生素E的补充剂,用于研究在葡聚糖硫酸钠(DSS)诱导的结肠炎中添加抗氧化剂或维生素E是否能够减少炎性肠病的有害影响。

生化/生理作用

α-由于具有抗氧化性质,生育酚还是一种自由基链断裂剂。
生育酚是一种脂溶性抗氧化剂,可保护细胞膜免受氧化损伤。α-生育酚是优先被人类吸收的生育酚的形式。DL-α-生育酚乙酸酯可抑制亚油酸的氧化。

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

No data available

閃點(°C)

No data available

個人防護裝備

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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alpha-Tocopherol stereoisomers
Jensen S K and Lauridsen C
Vitamins and Hormones, 76(3), 281-308 (2007)
Julie Carrier et al.
The Journal of nutrition, 132(10), 3146-3150 (2002-10-09)
Inflammatory bowel disease is often associated with iron deficiency anemia and oral iron supplementation may be required. However, iron may increase oxidative stress through the Fenton reaction and thus exacerbate the disease. This study was designed to determine in rats
S Grossman et al.
The International journal of biochemistry, 16(3), 281-289 (1984-01-01)
The formation of alpha-tocopherol--lipoxygenase complex was elucidated using immobilized affinity purified soybean lipoxygenase and [D-3H]alpha-tocopherol. The alpha-tocopherol--lipoxygenase complex did not dissociate on addition of linoleic acid. Iodoacetate modified immobilized lipoxygenase did not form the complex with alpha-tocopherol. Lipoxygenase attached to
Molecular mechanism of alpha-tocopherol action
Azzi A
Free radical biology & medicine, 43(1), 16-21 (2007)
Absorption, transport, and tissue delivery of vitamin E
Rigotti A
Molecular Aspects of Medicine, 28(5-6), 423-436 (2007)

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