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Merck
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主要文件

MABN663

Sigma-Aldrich

Anti-STMN2 Antibody, clone L5/1

clone L5/1, from mouse

别名:

Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

L5/1, monoclonal

物種活性

rat, human

物種活性(以同源性預測)

mouse (based on 100% sequence homology)

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

同型

IgG2bκ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

一般說明

Stathmin-like 2 (STMN2) protein is a phospho-protein and functions in microtubule dynamics and signal transduction. Studies show STMN2 plays a regulatory role in neuronal growth and thought to be involved in osteogenesis. Reduced levels, i.e. reduction in expression, have been associated with Down′s syndrome and Alzheimer′s disease. Data also suggests that STMN2 may play a role in modulating membrane interaction with the cytoskeleton during neurite outgrowth.

免疫原

Epitope: C-terminus
Linear peptide corresponding to the C-terminus of rat STMN2.

應用

Detect STMN using this mouse monoclonal antibody, Anti-STMN2 Antibody, clone L5/1 validated for use in western blotting, IHC & ICC.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected STMN2 in 10 µg of rat fetal brain (E16) tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected STMN2 in rat hippocampus tissue.
Immunocytochemistry Analysis: A representative lot detected STMN2 in cultured hippocampal neurons (Prof. J. Trimmer, University of Califnornia, Davis.).

品質

Evaluated by Western Blotting in SH-SY-5Y cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected STMN2 in 10 µg of SH-SY-5Y cell lysate.

標靶描述

~21 kDa observed

外觀

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Daisuke Aoki et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(4), 1473-1480 (2009-02-21)
Of the various microtubule-associated molecules, beta-tubulin III has been reported to be closely associated with the therapeutic efficacy of taxane-based chemotherapy against ovarian cancer. Stathmin and microtubule-associated protein 4 (MAP4) have been reported to play an important role in microtubule

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