推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
2H12, monoclonal
物種活性
rat, pig, mouse, human
製造商／商標名
Chemicon®
技術
flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG2a
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... BCL2L1(598)
一般說明
Bcl-X has two isoforms, Bcl-XL (long), a 241-aa protein, and Bcl-XS (short), a 178-aa protein lacking a 63 aa domain that is well conserved among members of the Bcl-2 family.
特異性
MAB4625 recognizes a protein of 27 kDa, identified as the Bcl-X protein. Reacts with both Bcl-XS and Bcl-XL.
免疫原
Synthetic peptide, aa 3-14 of human Bcl-X protein. This amino acid sequence is shared by human and murine Bcl-X protein.
應用
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
BCL2 & Inhibition
This Anti-Bcl-X Antibody, clone 2H12 is validated for use in FC, IF, IP, WB, IH for the detection of Bcl-X.
Wstern Blot: 1μg/mL (Hsu, 1997a; Hsu, 1997b)
Flow Cytometry
Immunofluorescence Immunoprecipitation: native protein (2ug/mg protein lysate).
Immunohistochemistry (frozen and paraffin): 2-4ug/mL for 30 minutes at room temperature.
Optimal working dilutions must be determined by end user.
Flow Cytometry
Immunofluorescence Immunoprecipitation: native protein (2ug/mg protein lysate).
Immunohistochemistry (frozen and paraffin): 2-4ug/mL for 30 minutes at room temperature.
Optimal working dilutions must be determined by end user.
外觀
Format: Purified
Protein A purified immunoglobulin in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
儲存和穩定性
Maintain at 2-8°C for up to 12 months.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
Anke H Sillars-Hardebol,Beatriz Carvalho,Jeroen Am Belien,Meike de Wit et al.
The Journal of Pathology null
Carles Solà-Riera et al.
PLoS pathogens, 16(2), e1008297-e1008297 (2020-02-08)
Hantaviruses, zoonotic RNA viruses belonging to the order Bunyavirales, cause two severe acute diseases in humans, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantavirus-infected patients show strong cytotoxic lymphocyte responses and hyperinflammation; however, infected cells remain
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