推荐产品
生物源
mouse
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
R6G9, monoclonal
物種活性
human
製造商／商標名
Chemicon®
技術
flow cytometry: suitable
immunoprecipitation (IP): suitable
同型
IgG2a
適合性
not suitable for Western blot
not suitable for activity/function inhibition
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... ITGB6(3694)
相关类别
特異性
Monoclonal antibody MAB2075Z, raised by immunizing Balb/c mice with murine NIH 3T3 cells stably transfected with the human beta6 subunit, recognizes the human beta6 subunit by flow cytometry and is an excellent antibody for immunoprecipitation.
免疫原
Murine NIH 3T3 cells stably transfected with the human (6 subunit
應用
Anti-Integrin β6 Antibody, clone R6G9, azide free is an antibody against Integrin β6 for use in FC & IP.
Flow cytometry
Immunoprecipitation: Effective; however because this antibody is an IgG2a, protein G or rabbit anti-mouse IgG is helpful for capture.
Immunohistochemistry/immunocytochemistry: The antibody recognizes alphaVbeta6 by immunohistochemistry and immunocytochemistry (acetone fix), but nuclear background staining limits usefulness in these techniques.
Then antibody is not function blocking and not effective for western blot.
Optimal working dilutions must be determined by end user.
Immunoprecipitation: Effective; however because this antibody is an IgG2a, protein G or rabbit anti-mouse IgG is helpful for capture.
Immunohistochemistry/immunocytochemistry: The antibody recognizes alphaVbeta6 by immunohistochemistry and immunocytochemistry (acetone fix), but nuclear background staining limits usefulness in these techniques.
Then antibody is not function blocking and not effective for western blot.
Optimal working dilutions must be determined by end user.
外觀
Format: Purified
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Alison Burman et al.
Journal of virology, 80(19), 9798-9810 (2006-09-16)
Foot-and-mouth disease virus (FMDV) can use a number of integrins as receptors to initiate infection. Attachment to the integrin is mediated by a highly conserved arginine-glycine-aspartic acid (RGD) tripeptide located on the GH loop of VP1. Other residues of this
A Weinacker et al.
The Journal of biological chemistry, 269(9), 6940-6948 (1994-03-04)
The integrin alpha v beta 6 has been shown to be a fibronectin-binding protein. To determine whether the cytoplasmic and transmembrane domains of alpha v beta 6 are necessary for binding to fibronectin, a truncated, secreted form of the integrin
Liudmila S Chesnokova et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(48), 20464-20469 (2009-11-19)
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is causally implicated in the development of lymphoid and epithelial tumors. Entry of virus requires fusion of virus envelopes and cell membranes. Fusion with B lymphocytes requires virus glycoprotein gB and
John J Grzesiak et al.
International journal of cancer, 129(12), 2905-2915 (2011-04-15)
To address the role of β(1) integrins in pancreatic cancer progression, we stably knocked down β(1) integrin subunit expression in human FG-RFP pancreatic cancer cells using lentiviral-based RNA interference. We then examined the effects of β(1) integrin
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