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Merck
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主要文件

AB1572

Sigma-Aldrich

Anti-GABA Transporter-2 Antibody

Chemicon®, from rabbit

别名:

GAT-2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

mouse, rat

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

特異性

GABA Transporter-2 (GAT-2), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected.

免疫原

GAT-2, C-terminus (aa 593-602)

應用

Immunohistochemistry: 1:500-1:750 on 4% paraformaldehyde fixed tissue.

It is recommended that the antibody is diluted in PBS containing 10% normal goat serum and 0.5% Triton X-100. AB1572 has been used for light microscopic studies of the rat nervous system.

Western blot: It has been reported that this antibody works for Western blot (Conti, 1999).

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
This Anti-GABA Transporter-2 Antibody is validated for use in IH, WB for the detection of GABA Transporter-2.

外觀

Affinity purified antibody. Purified in PBS with 0.1% sodium azide.

儲存和穩定性

Maintain lyophilized material at 2-8°C for up to 12 months. Maintain reconstituted material at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Hong Lin et al.
Disease models & mechanisms, 10(12), 1529-1538 (2017-12-21)
Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder with progressive ataxia that affects both the peripheral and central nervous system (CNS). While later CNS neuropathology involves loss of large principal neurons and glutamatergic and GABAergic synaptic terminals in the
Maria Elisa Calcagnotto et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(17), 7596-7605 (2002-08-28)
Children with brain malformations often exhibit an intractable form of epilepsy. Although alterations in cellular physiology and abnormal histology associated with brain malformations has been studied extensively, synaptic function in malformed brain regions remains poorly understood. We used an animal
J Johnson et al.
The Journal of comparative neurology, 375(2), 212-224 (1996-11-11)
gamma-Aminobutyric acid (GABA) plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. The distribution and cellular localization of GAT-1, GAT-2, and GAT-3 in the rat retina have been evaluated by using affinity-purified polyclonal antibodies directed

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