614350

Tomatidine, HCl

A steroidal alkaloid that structurally resembles Cyclopamine, but lacks the capacity to inhibit Shh (Sonic Hedgehog) signaling. Reported to be non-teratogenic.

• 别名: Tomatidine, HCl
• 经验公式（希尔记法）: C₂₇H₄₅NO₂ · xHCl
• CAS号: 6192-62-7
• 分子量: 415.65 (free base basis)
• MDL號碼: MFCD00133866
• 分類程式碼代碼: 12352200

属性

• 品質等級: 100
• 化驗: ≥90% (TLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic); protect from light
• 顏色: off-white
• 溶解度: DMF: 2 mg/mL; DMSO: 2 mg/mL; ethanol: 2.5 mg/mL; chloroform: methanol (1:1): 50 mg/mL
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• InChI: 1S/C27H45NO2.ClH/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4;/h16-24,28-29H,5-15H2,1-4H3;1H/t16-,17-,18-,19-,20+,21-,22-,23-,24-,25-,26-,27+;/m0./s1
• InChI 密鑰: SXXHVPYRDFJKPG-XRWUXUKGSA-N

说明

一般說明

A steroidal alkaloid that structurally resembles Cyclopamine (Cat. No. 239803), but lacks the capacity to inhibit Shh (Sonic Hedgehog) signaling. Reported to be non-teratogenic.

A steroidal alkaloid that structurally resembles Cyclopamine (Cat. No. 239803), but lacks the capacity to inhibit Sonic Hedgehog (Shh) signaling. Reported to be non-teratogenic. Useful as a negative control.

生化／生理作用

Cell permeable: no

Primary Target
Negative control for Shh (Sonic Hedgehog) signaling

Product does not compete with ATP.

Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

準備報告

Slight warming may be required to achieve complete solubilization.

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Berman, D.M., et al. 2003. Nature,425, 846.
Thayer, S.P., et al. 2003. Nature,425, 851.
Watkins, D.N., et al. 2003. Nature422, 313.
Cooper, M.K., et al. 1998. Science280, 1603.
Kim, S.K. and Melton, D.A. 1998. Proc. Natl. Acad. Sci. USA95, 13036.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable