推荐产品
品質等級
化驗
≥95% (HPLC)
形狀
liquid
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
desiccated (hygroscopic)
protect from light
運輸包裝
ambient
儲存溫度
−20°C
一般說明
A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). The solid form of this compound (Cat. No. 573102) is also available.
包裝
Packaged under inert gas
警告
Toxicity: Irritant (B)
外觀
A 50 mM (5 mg/274 µl) solution of STAT3 Inhibitor VI, S3I-201 (Cat. No. 573102) in DMSO.
重構
Following initial thaw, aliquot and freeze (-20°C).
其他說明
Lin, L., et al. 2009. Oncogene, 28, 961.
Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA104, 7391.
Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA104, 7391.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
188.6 °F - closed cup - (refers to pure substance)
閃點（°C）
87 °C - closed cup - (refers to pure substance)
Nina L Kikel-Coury et al.
PLoS biology, 19(11), e3001444-e3001444 (2021-11-19)
Glial cells are essential for functionality of the nervous system. Growing evidence underscores the importance of astrocytes; however, analogous astroglia in peripheral organs are poorly understood. Using confocal time-lapse imaging, fate mapping, and mutant genesis in a zebrafish model, we
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