218750

Caspase-3 Inhibitor III

The Caspase-3 Inhibitor III, also referenced under CAS 285570-60-7, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.

• 别名: Caspase-3 Inhibitor III, Ac-DEVD-CMK
• 经验公式（希尔记法）: C₂₁H₃₁ClN₄O₁₁
• CAS号: 285570-60-7
• 分子量: 550.94
• 分類程式碼代碼: 12352200
• NACRES: NA.54

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: lyophilized solid; powder
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated
• 顏色: white to off-white
• 溶解度: 20% acetonitrile: 1 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A potent cell-permeable and irreversible inhibitor of caspase-3, a member of the ICE-CED-3 family of cysteine proteases.

A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10.

生化／生理作用

Cell permeable: yes

Primary Target
caspase-3, caspase-6, caspase-7, caspase-8, caspase-10

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

序列

Ac-Asp-Glu-Val-Asp-CMK

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

其他說明

Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197
Schrantz, N., et al. 1999. Cell Death Differ. 6, 445.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable