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Merck

878112P

Avanti

C16-18:1 PC

Avanti Research - A Croda Brand 878112P, powder

别名:

1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine

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About This Item

经验公式(希尔记法):
C42H84NO7P
CAS号:
分子量:
746.09
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 5 mg (878112P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 878112P

脂質類型

bioactive lipids
phosphoglycerides

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COCCCCCCCCCCCCCCCC)=O

一般說明

C16-18:1 PC, also called as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of platelet-activating factor (PAF) family of glycerophospholipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.

應用

C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used in the liposome binding assay. It may also be used as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS).

生化/生理作用

Platelet-activating factor (PAF), a lipid mediator acts as a pro-inflammatory agent that exhibits variety of biological and pharmacological effects.

包裝

5 mL Clear Glass Sealed Ampule (878112P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


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Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform
John J H Shin et al.
Developmental cell, 52(4), 461-476 (2020-01-14)
Phosphoinositides, diacylglycerolpyrophosphate, ceramide-1-phosphate, and phosphatidic acid belong to a unique class of membrane signaling lipids that contain phosphomonoesters in their headgroups having pKa values in the physiological range. The phosphomonoester headgroup of phosphatidic acid enables this lipid to act as

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