推荐产品
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 2.5 mL (841118C-25mg)
製造商/商標名
Avanti Polar Lipids 841118C
濃度
10 mg/mL (841118C-25mg)
脂質類型
phosphoglycerides
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O
一般說明
Phosphatidylethanolamine (PE) is a phospholipid found in all living organism. The egg yolk contains high levels of unsaturated PE which accounts to 83.10%. The phosphatidylethanolamine (PE) headgroup is a zwitterion, with a negatively charged phosphate group and positively charged free amine group.
應用
Egg Trans PE is suitable for use:
- in the incubation of platelets for phospholipid enrichment and quantification by ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)
- in the synthesis of isoketals-phosphatidylethanolamine (IsoK-PE)
- in the preparation of phospholipid vesicles for factor X activation studies
生化/生理作用
Phosphatidylethanolamine (PE) along with other phospholipids forms the backbone of biological membranes. PE is known to regulate autophagy. The autophagic membranes possesses PE with high degree of unsaturation. Egg yolk PE has high radical scavenging activity owing to antioxidant potential.
包裝
5 mL Clear Glass Sealed Ampule (841118C-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
does not flash
閃點(°C)
does not flash
Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake
Journal of biological and chemical chronicles, 288(41), 29670-29679 (2013)
Analytical characterization of the role of phospholipids in platelet adhesion and secretion
Analytical Chemistry, 87(1), 413-421 (2014)
Isoketals form cytotoxic phosphatidylethanolamine adducts in cells
Journal of Lipid Research, 51(5), 999-1009 (2010)
The
The Membranes of Cells, 22(3) (2016)
Journal of lipid research, 51(5), 999-1009 (2009-12-08)
Levuglandins and their stereo- and regio-isomers (termed isolevuglandins or isoketals) are gamma-ketoaldehydes (IsoK) that rapidly react with lysines to form stable protein adducts. IsoK protein adduct levels increase in several pathological conditions including cardiovascular disease. IsoKs can induce ion channel
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