860539P

C16 Glucosyl(β) Ceramide (d18:1/16:0)

Avanti Research^™ - A Croda Brand

• 别名: D-glucosyl-β-1,1′-N-palmitoyl-D-erythro-sphingosine
• 经验公式（希尔记法）: C₄₀H₇₇NO₈
• CAS Number: 74365-77-8
• 分子量: 700.04
• MDL號碼: MFCD22416657
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 形狀: powder
• 包裝: pkg of 1 × 25 mg (860539P-25mg); pkg of 1 × 5 mg (860539P-5mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand
• 脂質類型: sphingolipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
• InChI 密鑰: VJLLLMIZEJJZTE-NNTBDIJYSA-N

说明

一般說明

Glucosyl(β) Ceramide (β-GlcCer) is a naturally occurring glycolipid and an ubiquitous intracellular metabolite. It might be present in the endoplasmic reticulum or Golgi apparatus.

應用

C16 Glucosyl(β) Ceramide (d18:1/16:0) or D-glucosyl-β-1,1′-N-palmitoyl-D-erythro-sphingosine has been used as a stock solution for the in vitro treatment of bacteria and to study the role of sphingolipids on pulmonary Pseudomonas aeruginosa infections in cystic fibrosis (CF). It may be used in the quantification of lipid in green fluorescence protein (GFP) and fatty acid transport protein 4 (FATP4) cells using electrospray ionization tandem mass spectrometry (ESI-MS/MS).

生化／生理作用

Glucosyl(β) Ceramide (β-GlcCer) is an endogenous macrophage inducible C-type lectin (Mincle) ligand, which has immunostimulatory property. It also stimulates inflammatory and acquired immune responses on myeloid cells through Mincle. It is a potential biomarker in Gaucher′s disease. β-GlcCer regulates the function of natural killer T (NKT) lymphocytes and exhibits antimetastatic effects. A balanced level of intracellular β-GlcCer is essential for maintaining tissue homeostasis.

包裝

5 mL Amber Glass Screw Cap Vial (860539P-25mg)

5 mL Amber Glass Screw Cap Vial (860539P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 11 - Combustible Solids