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Merck

860501P

Avanti

C22神经酰胺(d18:1/22:0)

Avanti Research - A Croda Brand 860501P, powder

别名:

N-二十二烷酰-D-赤-鞘氨醇

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About This Item

经验公式(希尔记法):
C40H79NO3
CAS号:
分子量:
622.06
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (860501P-10mg)
pkg of 1 × 5 mg (860501P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 860501P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C40H79NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-40(44)41-38(37-42)39(43)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,38-39,42-43H,3-32,34,36-37H2,1-2H3,(H,41,44)/b35-33+/t38-,39+/m0/s1

InChI 密鑰

KEPQASGDXIEOIL-GLQCRSEXSA-N

一般說明

C22神经酰胺(d18:1/22:0)或N-山嵛酰-D-赤型-鞘氨醇是一种人工合成的、由鞘氨醇和山嵛酸组成的神经酰胺。

應用

C22神经酰胺(d18:1/22:0)已用于:
  • 作为标准品,用于通过高效液相色谱/串联质谱(LC/MS2)技术测定肌肉组织样品中的神经酰胺浓度
  • 作为鞘脂代谢物的定量分析标准品
  • 研究其对线粒体-胞浆应激反应(MCSR)诱发的影响

生化/生理作用

神经酰胺在细胞分化、增殖和凋亡调节中起重要作用。还能调节应激和炎症反应。

包裝

5 mL棕色玻璃螺旋盖样品瓶(860501P-10mg)
5 mL棕色玻璃螺旋盖样品瓶(860501P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding diseases such as Alzheimer's, Parkinson's, and Huntington's. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work in parallel to ensure cellular
Donato A Rivas et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(11), 1727-1736 (2012-10-09)
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Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor

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