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Merck

43799

Sigma-Aldrich

N-棕榈酰-D-鞘氨醇

≥98.0% (TLC)

别名:

Cer(d18:1/16:0), (2S,3R,4E)-2-(棕榈酰氨基)-4-十八碳烯-1,3-二醇, N-[(1S,2R,3E)-2-羟基-1-(羟甲基)-3-庚烯-1-基]十六烷酰胺, N-棕榈酰-D-赤型-鞘氨醇, N-棕榈酰-D-鞘氨醇, C16-神经酰胺, C16神经酰胺(d18:1/16:0)

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About This Item

经验公式(希尔记法):
C34H67NO3
CAS号:
分子量:
537.90
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.85

化驗

≥98.0% (TLC)

形狀

powder or solid

成份

carbon content, 75.92%
hydrogen content, 12.55%
nitrogen content, 2.60%

官能基

amide

脂質類型

sphingolipids

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1

InChI 密鑰

YDNKGFDKKRUKPY-TURZORIXSA-N

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Gloria I Perez et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(7), 860-862 (2005-02-25)
An age-dependent acceleration of apoptosis occurs in female germ cells (oocytes), and this requires communication between the oocyte and its surrounding somatic (cumulus) cells. Here we show in aged mice that ceramide is translocated from cumulus cells into the adjacent
S White-Gilbertson et al.
Oncogene, 28(8), 1132-1141 (2009-01-13)
We have previously shown that the death receptor ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces an increase of intracellular C(16)-ceramide in sensitive SW480 but not in resistant SW620 cells. Resistance in SW620 cells was overcome by exogenous ceramide, leading
Claudia Almeida et al.
PloS one, 13(8), e0201373-e0201373 (2018-08-11)
Biological membranes contain a large variety of lipids species compartmentalized in different domains heterogeneous in size, composition and dynamics. Cholesterol induces membrane ordered domains thanks to its affinity for saturated lipids. Membrane domains had been studied with fluorescent probes either
Daniel Dindo et al.
Molecular cancer therapeutics, 5(6), 1520-1529 (2006-07-05)
Ceramides are sphingolipid second messengers that are involved in the mediation of cell death. There is accumulating evidence that mitochondria play a central role in ceramide-derived toxicity. We designed a novel cationic long-chain ceramide [omega-pyridinium bromide D-erythro-C16-ceramide (LCL-30)] targeting negatively
Jérôme Becam et al.
Scientific reports, 7(1), 17627-17627 (2017-12-17)
Certain fatty acids and sphingoid bases found at mucosal surfaces are known to have antibacterial activity and are thought to play a more direct role in innate immunity against bacterial infections. Herein, we analysed the antibacterial activity of sphingolipids, including

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