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化驗
99% (TLC)
形狀
powder
包裝
package of 1 × 100 μg (850188P-100UG)
package of 1 × 500 μg (850188P-500UG)
製造商/商標名
Avanti Polar Lipids
脂質類型
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](OP(O)([O-])=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
一般說明
PI(3,4)P2 is a lipid secondary messenger. It is obtained from the dephosphorylation of PI(3,4,5)P3 by 5-phosphatase.
生化/生理作用
PI(3,4)P2 plays a role in protein kinase B (PKB) phosphorylation on Ser473 in mast cells. It also binds to certain effectors such as serine/threonine-specific protein kinase (AKT) and dual adaptor of phosphotyrosine and 3-phosphoinositides 1 (DAPP1). It also regulates the activity of actin mesh which is associated with endocytic structures.
包裝
2 mL Amber Serum Vial with Stopper and Crimp Cap (850188P-100UG)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850188P-500UG)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850188P-500UG)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
PTEN regulates PI (3, 4) P2 signaling downstream of class I PI3K
Molecular Cell, 68(3), 566-580 (2017)
PI (3, 4, 5) P3 and PI (3, 4) P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser473, respectively; PI (3, 4) P2 levels determine PKB activity
Cellular Signalling, 20(4), 684-694 (2008)
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