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Merck

840037P

Avanti

16:0 PS

Avanti Research - A Croda Brand

别名:

1,2-二十六烷酰基-sn-甘油-3-磷酸-L-丝氨酸(钠盐);DPPS;PS(16:0/16:0);110668

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About This Item

经验公式(希尔记法):
C38H73NO10PNa
分子量:
757.95
MDL號碼:
分類程式碼代碼:
51191904
NACRES:
NA.25

描述

1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt)

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (840037P-10mg)
pkg of 1 × 200 mg (840037P-200mg)
pkg of 1 × 25 mg (840037P-25mg)
pkg of 1 × 500 mg (840037P-500mg)

製造商/商標名

Avanti Research - A Croda Brand

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C38H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45);/q;+1/p-1/t34-,35+;/m1./s1

InChI 密鑰

GTLXLANTBWYXGW-CEGNZRHUSA-M

一般說明

磷脂酰丝氨酸是一种在真核细胞中大量存在的阴离子磷脂。总细胞脂质的10%由磷脂酰丝氨酸组成。O-磷酸-L-丝氨酸是热稳定性底物。

應用

16:0 PS 已用于测定纯化动力学相关蛋白 1 (Drp1) 和合成脂质体之间互作的分析实验。
16:0 PS可用于脂质体浮选分析,用于测定其在纯化发动蛋白相关蛋白1(Drp1)之间的相互作用,并可作为制备单层脂质体的脂质混合物的成分。它还被用于通过脂膜水化法制备脂质体。

生化/生理作用

磷脂酰丝氨酸(PtdSer)参与各种细胞内信号通路。它还在细胞凋亡和血液凝固中起主要作用。

包裝

20 mL 螺旋盖透明玻璃瓶 (840037P-200mg)
30 mL 螺旋盖棕色宽口瓶 (840037P-500mg)
5 mL 螺旋盖透明玻璃瓶 (840037P-10mg)
5 mL 螺旋盖透明玻璃瓶 (840037P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Condensation of Model Lipid Films by Cholesterol: Specific Ion Effects
Martimathin-MA, et al.
Coatings, 9(8), 474-474 (2020)
Assay to Measure Interactions between Purified Drp1 and Synthetic Liposomes
Adachi Y, et al.
Bio-protocol, 7(9) (2017)
Ana Cristina Racca et al.
Frontiers in oncology, 9, 544-544 (2019-07-06)
Tumor cells require high rates of lipid synthesis to support membrane biogenesis for their exacerbated growth. The only two proteins known that activate phospholipid synthesis are Fra-1 and c-Fos, two members of the AP-1 family of transcription factors. These proteins
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Tetiana Mukhina et al.
The journal of physical chemistry letters, 10(22), 7195-7199 (2019-11-05)
We investigate the interaction between highly charged lipid bilayers in the presence of monovalent counterions. Neutron and X-ray reflectivity experiments show that the water layer between like-charged bilayers is thinner than for zwitterionic lipids, demonstrating the existence of counterintuitive electrostatic

Global Trade Item Number

货号GTIN
840037P-25MG4061835228713
840037P-10MG4061835228690
840037P-200MG4061835228706
840037P-500MG4061835228720

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