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描述
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt)
化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 10 mg (790404P-10mg)
pkg of 1 × 25 mg (790404P-25mg)
pkg of 1 × 5 mg (790404P-5mg)
製造商/商標名
Avanti Research™ - A Croda Brand
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
1,2-二油酰基-sn-甘油基-3-[(N-(5-氨基-1-羧基戊基)亚氨基二乙酸)琥珀酰基]氮川三乙酸(NTA)(18:1 DGS-NTA(Ni))是含镍的共轭磷脂 。NTA与镍离子中存在六个配位点中的四个螯合。
應用
1,2-二油酰基-sn-甘油基-3-[(N-(5-氨基-1-羧基戊基)亚氨基二乙酸)琥珀酰基](镍盐)(18:1 DGS-NTA(Ni))用于:
- 制备含卟啉-磷脂(PoP)偶联物的脂质体,用于蛋白质和肽的结合研究
- 制备纳米级多层囊泡(NMV),用于抗原递送研究
- 作为小单层囊泡(SUV)成分,用于制备平面脂质膜(PM)
生化/生理作用
1,2-二油酰基-sn-甘油基-3-[(N-(5-氨基-1-羧基戊基)亚氨基二乙酸)琥珀酰基]氮川三乙酸(NTA)(18:1 DGS-NTA(Ni))可用于结构生物学,尤其适合重组组氨酸标签结合蛋白。 虽然用处很大,但纳米颗粒在生物样品中存在稳定性问题。因此,NTA-脂质缀合物主要用作脂质体或纳米颗粒涂层。基于DGS-NTA(Ni)的纳米级多层囊泡(NMV)是有效的疫苗递送系统。
包裝
5 mL透明玻璃密封安瓿(790404P-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
其他客户在看
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