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Key Documents

700092P

Avanti

campesterol-d6

campesterol-d6, powder

别名:

26,27-hexadeuteriocampest-5-en-3β-ol; 111018

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About This Item

经验公式(希尔记法):
C28H42D6O
分子量:
406.72
分類程式碼代碼:
41141804
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (700092P-1mg)

製造商/商標名

Avanti Research - A Croda Brand 700092P

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

Campesterol-d6 is the deuterated form of campesterol. It is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure. It is not synthesized in mammanls and is diet derived

應用

Campesterol-d6 has been used as a deuterium-labeled internal standard in gas chromatography (GC)–triple quadrupole mass spectrometry and liquid chromatography-high resolution mass spectrometry (LC-HRMS).

生化/生理作用

Campesterol reduces the levels of chylomicron. The d6-campesterol along with d6-sitosterol and d6-cholesterol has been used in the transport blood-brain barrier studies in human brain endothelial hCMEC/D3 monolayer cells. Campesterol is a biomarker for tracking cholesterol synthesis and absorption. Campesterol like cholesterol is catabolized by intestinal microbes. It possess chemopreventive functionality prostate and breast tumors. Campesterol also has antiangiogenic property and may be useful in treating disorders related to angiogenesis.

包裝

5 mL Amber Glass Screw Cap Vial (700092P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Alan H B Wu et al.
Clinica chimica acta; international journal of clinical chemistry, 430, 43-47 (2014-01-08)
The analysis of blood for β-sitosterol and campesterol is the measures of cholesterol absorption while lathosterol is a measure of cholesterol synthesis. The biological variability of β-sitosterol, campesterol, and lathosterol was measured using liquid-chromatography tandem mass spectrometry from a cohort

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