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Merck

O5504

Sigma-Aldrich

齐墩果酸

≥97%

别名:

(+)-Oleanolic acid, 3beta-Hydroxyolean-12-en-28-oic acid, Astrantiagenin C, Caryophyllin, Oleanic acid

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About This Item

经验公式(希尔记法):
C30H48O3
CAS号:
分子量:
456.70
EC號碼:
MDL號碼:
分類程式碼代碼:
12352002
PubChem物質ID:
NACRES:
NA.22

化驗

≥97%

形狀

powder

顏色

light yellow

mp

>300 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O

InChI

1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1

InChI 密鑰

MIJYXULNPSFWEK-GTOFXWBISA-N

基因資訊

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一般說明

齐墩果酸是羟基五环三萜酸(HPTA),具有抗菌、抗肿瘤和抗利尿作用。

應用

齐墩果酸在通过高效薄层色谱(HPTLC)在锡生藤属锡生藤的根中进行定量时,被用作参考化合物。

生化/生理作用

从药用植物分离的三萜类化合物。抗肿瘤和保肝剂。齐墩果酸具有治疗神经退行性疾病的潜力。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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In this study, an in-depth analysis of the unique set of rosehip samples from 71 Rosa genotypes was conducted with the aim to identify the most suitable ones for applications in the food and pharmaceutical industries based on the content
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Oleanolic acid (OA) as an antileishmanial agent: Biological evaluation and in silico mechanistic insights.
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Li Chen et al.
Journal of medicinal chemistry, 51(15), 4834-4838 (2008-07-05)
Novel furoxan-based nitric oxide (NO) releasing derivatives of oleanolic acid (OA) were synthesized for potential therapy of liver cancers. Six compounds produced high levels of NO in human hepatocellular carcinoma (HCC) cells and exhibited strong cytotoxicity selectively against HCC in
Amélia M Silva et al.
Pharmaceutics, 11(8) (2019-07-28)
Oleanolic (OA) and ursolic (UA) acids are recognized triterpenoids with anti-cancer properties, showing cell-specific activity that can be enhanced when loaded into polymeric nanoparticles. The cytotoxic activity of OA and UA was assessed by Alamar Blue assay in three different

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