推荐产品
品質等級
化驗
≥98%
SMILES 字串
Br[H].CCCN(CCC)C1CCc2cccc(O)c2C1
InChI
1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H
InChI 密鑰
BATPBOZTBNNDLN-UHFFFAOYSA-N
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應用
(±)-8-羟基-2-（二丙基氨基）四氢溴酸盐是一种强效的选择性 5-羟色胺 (5HT 1A )-受体激动剂 ，通常作为药理学研究的标准。
生化／生理作用
选择性 5-HT1 激动剂，对亚型 5-HT1A 受体具有高亲和性。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Arylpiperazine agonists of the serotonin 5-HT 1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2.
Stroth N, et al.
Bioorganic & Medicinal Chemistry, 23(15), 4824-4830 (2015)
8-Hydroxy-2-(di-n-propylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist.
L E Arvidsson et al.
Journal of medicinal chemistry, 24(8), 921-923 (1981-08-01)
S J Peroutka
Journal of neurochemistry, 47(2), 529-540 (1986-08-01)
Drug interactions with 5-HT1 (5-hydroxytryptamine type 1) binding site subtypes were analyzed in rat frontal cortex. 8-Hydroxy-N,N-dipropyl-2-aminotetralin (8-OH-DPAT) displays high affinity (Ki 3.3 +/- 1 nM) for 29 +/- 3% of total [3H]5-HT binding in rat frontal cortex and low
Improved preparation, chromatographic separation and X-ray crystallographic determination of the absolute configuration of the enantiomers of 8-hydroxy-2-(dipropylamino) tetralin (8-OH DPAT).
Karlsson A, et al.
Acta Chemica Scandinavica, 42, 231-236 (1988)
8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site.
D N Middlemiss et al.
European journal of pharmacology, 90(1), 151-153 (1983-05-20)
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