推荐产品
产品名称
α-甲基- DL -色氨酸, crystalline
化驗
≥98% (TLC)
品質等級
形狀
crystalline
技術
tissue culture: suitable
顏色
light yellow
儲存溫度
2-8°C
SMILES 字串
CC(N)(Cc1c[nH]c2ccccc12)C(O)=O
InChI
1S/C12H14N2O2/c1-12(13,11(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,14H,6,13H2,1H3,(H,15,16)
InChI 密鑰
ZTTWHZHBPDYSQB-UHFFFAOYSA-N
相关类别
應用
- 通过剥夺谷氨酰胺和级联血栓形成纳米工程声敏血小板协同增强声动力学肿瘤治疗: 该研究探索了使用α-甲基- DL -色氨酸，通过剥夺谷氨酰胺和诱发血栓形成来增进声动力学肿瘤治疗的效果，为癌症治疗提供了一条新途径（Zhou et al., 2023）。
- 靶向转运蛋白的加替沙星前药：合成、渗透性和眼睛局部给药: 该论文介绍了α-甲基- DL -色氨酸在靶向转运蛋白的前药开发中的应用， 改善了药物递送系统，特别是眼科治疗中的药物递送系统（Vooturi et al., 2012）。
- SLC6A14（ATB0,+）蛋白是一种高度集中的、具有广泛特异性的氨基酸转运蛋白，它是雌激素受体阳性乳腺癌治疗中有效的新型药物靶点。: 该研究考察了α-甲基- DL -色氨酸在雌激素受体阳性乳腺癌治疗中靶向 SLC6A14的作用，重点介绍了其成为治疗药的潜力（Karunakaran et al., 2011）。
生化／生理作用
α-甲基-DL-色氨酸是ATBo的阻滞剂，ATBo是一种氨基酸转运蛋白，其表达在癌症中上调。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Alexandre Berney et al.
Archives of general psychiatry, 68(7), 732-741 (2011-03-09)
The hypothesis of a serotonin (5-hydroxytryptamine [5-HT]) dysfunction in obsessive-compulsive disorder (OCD) stems largely from the clinical efficacy of 5-HT reuptake inhibitors. Serotonergic abnormalities in the unmedicated symptomatic state, however, remain to be fully characterized. To investigate brain regional 5-HT
Kazuya Kanemaru et al.
Neurochemistry international, 55(7), 529-535 (2009-05-26)
The neurotransmitter, serotonin, is involved in several brain functions, including both normal, physiological functions, and pathophysiological functions. Alterations in any of the normal parameters of serotonergic neurotransmission can produce several different psychiatric disorders, including major depression. In many instances, brain
Mario L Muscedere et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 198(3), 219-227 (2011-12-03)
As social insect workers mature, outside-nest tasks associated with foraging and defense are typically performed at higher frequencies. Foraging in ants is often a pheromonally mediated collective action performed by mature workers; age-dependent differences in olfactory response thresholds may therefore
Harry T Chugani et al.
Epilepsia, 52(9), 1692-1698 (2011-05-17)
Interictal increase of (11) C-alpha-methyl-l-tryptophan (AMT) on positron emission tomography (PET) can be seen in cortical epileptic foci, and is particularly common in cortical developmental malformations. Therefore, in the present study, we evaluated the clinical and histopathologic correlates of AMT-PET
Kazuya Kanemaru et al.
Brain research bulletin, 77(4), 214-220 (2008-08-05)
In this study, we measured the effect of an acute treatment of citalopram on 5-hydroxytryptamine (5-HT) synthesis in a genetic rat model of depression, the Flinders Sensitive Line (FSL) rats, their counterparts, the Flinders Resistant Line (FRL) rats, and outbred
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