A59654

5-氨基吲哚

97%

• 别名: 5-吲哚胺
• 经验公式（希尔记法）: C₈H₈N₂
• CAS号: 5192-03-0
• 分子量: 132.16
• Beilstein: 112348
• EC號碼: 225-977-2
• MDL號碼: MFCD00005679
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24891044
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: 97%
• 形狀: crystals
• mp: 131-133 °C (dec.) (lit.)
• SMILES 字串: Nc1ccc2[nH]ccc2c1
• InChI: 1S/C8H8N2/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,9H2
• InChI 密鑰: ZCBIFHNDZBSCEP-UHFFFAOYSA-N

说明

應用

Reactant for preparation of:

• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP
• Cytotoxic and antimitotic agents
• Insulin-like growth factor 1 receptor inhibitors
• Antitumoral agents
• Factor Xa inhibitor
• Potential antivascular agents
• Gli1-mediated transcription in the Hedgehog pathway
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects
• PKCθ inhibitors
• HIV protease inhibitors

安全信息

• 象形圖: GHS06,GHS09
• 訊號詞: Danger
• 危險聲明: H302,H311,H319,H400
• 防範說明: P264 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves